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SH3D19 encodes a multiple SH3 domain-containing protein, which interacts with other proteins, such as EBP and members of ADAM family, via the SH3 domains. Additionally we are shipping SH3D19 Antibodies (20) and and many more products for this protein.
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identified and characterized EBP (show EBP Proteins), a novel EEN binding protein that interacts with the SH3 domain (show ITSN1 Proteins) of EEN (show SH3GL1 Proteins); normally expressed in cytoplasm but recruited to the nucleus by MLL (show MLL Proteins)-EEN (show SH3GL1 Proteins) [EBP (show EBP Proteins)]
yeast two-hybrid screening using the cytoplasmic domain of ADAM12 (show ADAM12 Proteins) as bait identified a protein designated Eve-1. Eve-1 plays a role in positively regulating the activity of ADAMs in the signaling of EGFR (show EGFR Proteins)-ligand shedding.
Sh3d19 transcripts in mouse skin expressed in accordance with hair cycle. Transcripts detected predominantly in medulla cells at level corresponding to keratogenous zone of hair follicles during mid and late anagen phases.
This gene encodes a multiple SH3 domain-containing protein, which interacts with other proteins, such as EBP and members of ADAM family, via the SH3 domains. This protein may be involved in suppression of Ras-induced cellular transformation and Ras-mediated activation of ELK1 by EBP, and regulation of ADAM proteins in the signaling of EGFR-ligand shedding. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
SH3 domain protein D19
, SH3 domain-containing protein 19
, SH3 domain containing 19
, ADAM-binding protein Eve-1
, EEN-binding protein
, SH3 domain containing protein D 19