SHANK2 Proteins
SHANK2 encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD).
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SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 1-1470) protein (His tag) Protein
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 1-1476) protein (His tag) Protein
SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2) (AA 1034-1124) protein (GST tag) Protein
SHANK2 Protein Profile
Protein Summary
This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined.
Gene names and symbols associated with SHANK2
- SH3 and multiple ankyrin repeat domains 2 (SHANK2) antibody
- SH3 and multiple ankyrin repeat domains 2 (Shank2) antibody
- SH3 and multiple ankyrin repeat domains 2 L homeolog (shank2.L) antibody
- SH3 and multiple ankyrin repeat domains 2 (shank2) antibody
- SH3 and multiple ankyrin repeat domains protein 2 (LOC100438523) antibody
- auts17 antibody
- CortBP1 antibody
- cttnbp1 antibody
- MGC122482 antibody
- mKIAA1022 antibody
- prosap1 antibody
- SHANK antibody
- SHANK2 antibody
- Spank-3 antibody
Protein level used designations for SHANK2
GKAP/SAPAP interacting protein , SH3 and multiple ankyrin repeat domains protein 2 , cortactin SH3 domain-binding protein , cortactin-binding protein 1 , proline-rich synapse associated protein 1 , proline-rich synapse-associated protein 1 , cortBP1 , SH3 and multiple ankyrin repeat domains 2 , SH3/ankyrin domain gene 2 , SH3 and multiple ankyrin repeat domains protein 2-like , GKAP/SAPAP-interacting protein , proline rich synapse associated protein 1
GENE ID | SPECIES |
---|---|
22941 | Homo sapiens |
210274 | Mus musculus |
428858 | Gallus gallus |
483677 | Canis lupus familiaris |
734458 | Xenopus laevis |
100124731 | Xenopus (Silurana) tropicalis |
100338286 | Oryctolagus cuniculus |
100412179 | Callithrix jacchus |
171093 | Rattus norvegicus |
466694 | Pan troglodytes |
618649 | Bos taurus |
708192 | Macaca mulatta |
100031879 | Monodelphis domestica |
100438523 | Pongo abelii |
100579795 | Nomascus leucogenys |
100732196 | Cavia porcellus |
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