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SHC (Src Homology 2 Domain Containing) Family, Member 4 Proteins (SHC4)

Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Additionally we are shipping SHC (Src Homology 2 Domain Containing) Family, Member 4 Antibodies (58) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat SHC4 SHC4 679845  
SHC4 399694 Q6S5L8
SHC4 271849 Q6S5L9
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Top SHC (Src Homology 2 Domain Containing) Family, Member 4 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$8,498.50
Details
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$860.20
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SHC4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine)

More Proteins for SHC (Src Homology 2 Domain Containing) Family, Member 4 (SHC4) Interaction Partners

Human SHC (Src Homology 2 Domain Containing) Family, Member 4 (SHC4) interaction partners

  1. ShcD binds to active Ret (show RET Proteins), TrkA (show NTRK1 Proteins), and TrkB (show NTRK2 Proteins) neurotrophic factor (show NTF3 Proteins) receptors predominantly via its phosphotyrosine-binding (PTB (show PTBP1 Proteins)) domain.

  2. The ShcD signaling adaptor facilitates ligand-independent phosphorylation of the EGF receptor (show EGFR Proteins).

  3. ShcD can exist within the nucleus, and its CH2 (show Acyp1 Proteins) domain has a critical role in nuclear export of ShcD.

  4. ShcD binds to TrkC in a kinase-activity-dependent manner through its PTB and SH2 domains.

  5. ShcD interacts with TrkB (show NTRK2 Proteins) in a kinase-activity-dependent manner.

  6. A new member of the Shc (show SHC1 Proteins) family of docking proteins is characterised, which may mediate a specific aspect of signaling downstream of the MuSK (show MUSK Proteins) receptor.

Mouse (Murine) SHC (Src Homology 2 Domain Containing) Family, Member 4 (SHC4) interaction partners

  1. Shc4 is an important modulator in the switch of key pathway(s) involved in determining epiblast stem cell identity.

  2. The unique tissue distribution patterns of Shc (show SHC1 Proteins) proteins likely contribute to their complex tissue-specific signaling functions during embryogenesis.

  3. A new member of the Shc (show SHC1 Proteins) family of docking proteins is characterised, which may mediate a specific aspect of signaling downstream of the MuSK (show MUSK Proteins) receptor.

SHC (Src Homology 2 Domain Containing) Family, Member 4 (SHC4) Protein Profile

Protein Summary

Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.

Gene names and symbols associated with SHC4

  • SHC adaptor protein 4 (Shc4)
  • SHC adaptor protein 4 (SHC4)
  • SHC (Src homology 2 domain containing) family, member 4 (Shc4)
  • 6230417E10Rik protein
  • 9930029B02Rik protein
  • Gm685 protein
  • RaLP protein
  • RGD1309182 protein
  • SHCD protein

Protein level used designations for SHC4

SHC-transforming protein 4 , SH2 domain protein C4 , SHC-transforming protein D , hShcD , rai-like protein , src homology 2 domain-containing-transforming protein C4 , mShcD , novel phosphotyrosine interaction domain (PTB/PID) and SH2 domains containing protein , rai-like protein RaLP

GENE ID SPECIES
679845 Rattus norvegicus
399694 Homo sapiens
271849 Mus musculus
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