anti-Shugoshin-Like 2 (S. Pombe) Antibodies

Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I.

Data Quality
  • 4
Type
  • 26
    Primary antibodies
Antigen
  • 26
Reactivity
  • 26
  • 1
Application
  • 19
  • 19
  • 4
  • 3
  • 2
Detection Method
  • 3
Host
  • 26
Clonality
  • 26
Binding Specificity
  • 17
  • 10
  • 8
  • 2
  • 1
Conjugate
  • 14
  • 2
  • 2
  • 2
  • 2
Isotype
  • 23
  • 2
Format
  • 26
Suggested next Filters
26 Products
ReactivityHuman
Application IF, IHC (p)
Order details Cat. No. ABIN5587828
$577.33
100 μL
Plus shipping costs $45.00
Delivery in 11 to 12 Business Days
ReactivityHuman
Application ELISA, IHC (p)
Order details Cat. No. ABIN6287322
$309.14
50 μL
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman
Application ELISA, IHC
Order details Cat. No. ABIN3186936
$369.83
Plus shipping costs $45.00
Delivery in 11 to 13 Business Days
ReactivityHuman
Application IHC, ELISA
Order details Cat. No. ABIN1535371
$324.50
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN5538697
$550.00
400 μL
Plus shipping costs $45.00
Delivery in 2 to 3 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN3001311
$640.17
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application ELISA, IHC
Order details Cat. No. ABIN6099031
$337.67
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN2795993
ISO
$467.50
400 μL
Plus shipping costs $45.00
Delivery in 6 to 8 Business Days
ReactivityHuman
Application ELISA, IHC, IHC (p)
Order details Cat. No. ABIN2884336
$493.17
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman
Application WB
Order details Cat. No. ABIN1805688
$493.17
400 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman, Monkey
Application IP
Order details Cat. No. ABIN1934414
$610.50
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman
Application IP, WB
Order details Cat. No. ABIN1934415
$610.50
100 μL
Plus shipping costs $45.00
Delivery in 11 to 14 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN2359658
$658.43
200 μL
Plus shipping costs $45.00
Delivery in 11 to 16 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN2359656
$814.00
200 μL
Plus shipping costs $45.00
Will be delivered in 16 Business Days
ReactivityHuman
Application ELISA, WB
Order details Cat. No. ABIN2359657
$814.00
200 μL
Plus shipping costs $45.00
Will be delivered in 16 Business Days
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Shugoshin-Like 2 (S. Pombe) (SGOL2) Antigen Profile

Protein Summary

Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.

Gene names and symbols associated with SGOL2

  • shugoshin 2 (SGO2) antibody
  • shugoshin 2A (Sgo2a) antibody
  • 1110007N04Rik antibody
  • 4932411A20Rik antibody
  • 5730576N04Rik antibody
  • AU018846 antibody
  • AV008062 antibody
  • D1Ertd8e antibody
  • SGO2 antibody
  • Tripin antibody

Protein level used designations for SGOL2

shugoshin-2 , shugoshin-like 2 , sgo2

GENE ID SPECIES
151246 Homo sapiens
68549 Mus musculus
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