anti-Sialic Acid Binding Ig-Like Lectin 11 (SIGLEC11) Antibodies

SIGLEC11 encodes a member of the sialic acid-binding immunoglobulin-like lectin family. Additionally we are shipping SIGLEC11 Proteins (3) and SIGLEC11 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SIGLEC11 114132 Q96RL6
SIGLEC11    
SIGLEC11    
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Top anti-SIGLEC11 Antibodies at antibodies-online.com

Showing 10 out of 60 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 4 to 8 Days
$522.50
Details
Human Goat PE FACS Detection of Siglec-11 in Human Peripheral Blood Mononuclear Cell Monocytes and Granulocytes by Flow Cytometry. Human peripheral blood mononuclear cell monocytes and granulocytes were stained with Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$352.56
Details
Human Rabbit Un-conjugated IHC (p), WB SIGLEC11 Antibody (ABIN388425) western blot analysis in MCF-7 cell line lysates (35 µg/lane).This demonstrates the SIGLEC11 antibody detected the SIGLEC11 protein (arrow). SIGLEC11 Antibody (C-term) (ABIN388425)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: SIGLEC11 Antibody [NBP2-32523] - Immunohistochemical staining of human cervix, uterine shows weak membranous positivity in squamous epithelial cells. Immunohistochemistry: SIGLEC11 Antibody [NBP2-32523] - liver cancer 0.1 mL Log in to see 10 to 13 Days
$494.38
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 100 μg Log in to see 11 to 14 Days
$551.83
Details
Human Mouse Un-conjugated CyTOF, FACS, IHC Detection of Siglec-11 in HEK293 Human Cell Line Transfected with Human Siglec-11 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with either (A) human Siglec-11 or (B) human Siglec-16 and eGFP was stained with Mouse Anti-Human Siglec-11 Monoclonal Antibody. Siglec-11 in Human Lymph Node. Siglec-11 was detected in immersion fixed paraffin-embedded sections of human lymph node using Mouse Anti-Human Siglec-11 Monoclonal Antibody. Tissue was stained using the Anti-Mouse HRP-DAB Cell & 100 μg Log in to see 8 to 9 Days
$299.45
Details
Human Goat Un-conjugated BR, FACS, WB Detection of Siglec-11 in Human PBMCs by Flow Cytometry. Human peripheral blood monocytes (PBMC) were labeled with Goat Anti-Human Siglec-11 Antigen Affinity-purified Polyclonal Antibody. 100 μg Log in to see 8 to 9 Days
$284.76
Details
Human Goat Biotin FACS, WB   50 μg Log in to see 8 to 9 Days
$323.18
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA   200 μL Log in to see 11 to 14 Days
$1,013.83
Details
Human Rabbit PE IHC, ELISA   200 μL Log in to see 11 to 14 Days
$1,013.83
Details

Top referenced anti-SIGLEC11 Antibodies

  1. Human Polyclonal SIGLEC11 Primary Antibody for IHC (p), ELISA - ABIN544604 : Angata, Kerr, Greaves, Varki, Crocker, Varki: Cloning and characterization of human Siglec-11. A recently evolved signaling molecule that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages, including brain microglia. in The Journal of biological chemistry 2002 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal SIGLEC11 Primary Antibody for FACS - ABIN4895909 : Madge, Maggioni, Pascolutti, Amin, Waespy, Bellette, Thomson, Kelm, von Itzstein, Haselhorst: Structural characterisation of high affinity Siglec-2 (CD22) ligands in complex with whole Burkitt's lymphoma (BL) Daudi cells by NMR spectroscopy. in Scientific reports 2016 (PubMed)

  3. Human Polyclonal SIGLEC11 Primary Antibody for FACS, WB - ABIN4899316 : Wang, Chow, Deng, Anderson, Weidner, Godwin, Bewtra, Zlotnik, Bui, Varki, Varki: Expression of Siglec-11 by human and chimpanzee ovarian stromal cells, with uniquely human ligands: implications for human ovarian physiology and pathology. in Glycobiology 2011 (PubMed)

More Antibodies against SIGLEC11 Interaction Partners

Human Sialic Acid Binding Ig-Like Lectin 11 (SIGLEC11) interaction partners

  1. The authors demonstrated that the human-specific pathogen Escherichia coli K1 uses its polysialic acid capsule as a molecular mimic to engage Siglec-11 and escape killing. In contrast, engagement of the activating counterpart Siglec-16 increases elimination of bacteria.

  2. The results indicate potential roles for Siglec-11 in ovarian physiology and human evolution.

  3. Siglec-11 ectopically expressed on murine microglia interacts with PSA on neurons, reduces LPS-induced gene transcription of proinflammatory mediators, impairs phagocytosis and alleviates microglial neurotoxicity.

  4. cloning and characterization; a recently evolved signaling that can interact with SHP-1 and SHP-2 and is expressed by tissue macrophages including brain microglia

  5. expressed in human but not in chimpanzee brain microglia; findings indicate that human SIGLEC11 emerged through human-specific gene conversion by an adjacent pseudogene

  6. SIGLEC16 encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non-functional alleles in humans.

SIGLEC11 Antigen Profile

Protein Summary

This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. This family member mediates anti-inflammatory and immunosuppressive signaling. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SIGLEC11

  • sialic acid binding Ig like lectin 11 (SIGLEC11) antibody

Protein level used designations for SIGLEC11

sialic acid-binding Ig-like lectin 11 , siglec-11 , sialic acid binding Ig-like lectin 11 , sialic acid-binding Ig-like lectin 11-like

GENE ID SPECIES
114132 Homo sapiens
747721 Pan troglodytes
100387822 Callithrix jacchus
100447534 Pongo abelii
100605002 Nomascus leucogenys
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