anti-Sialic Acid Binding Ig-Like Lectin E (Siglece) Antibodies

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Siglece 83382 Q91Y57
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Top anti-Siglece Antibodies at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rat Un-conjugated CyTOF, FACS Detection of Mouse Siglec-E in Mouse Splenocytes. Mouse Splenocytes were stained with Anti-Mouse Integrin alpha X/CD11c Phycoerythrin-conjugated Antibody and either (A) Rat IgG2B Isotype Control. 100 μg Log in to see 8 to 9 Days
$299.00
Details
Mouse Rat APC FACS Detection of Siglec-E in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Mouse Anti-Human CD11c PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$399.05
Details
Mouse Rat Alexa Fluor 405 FACS   0.1 mg Log in to see 10 to 13 Days
$490.19
Details
Mouse Rat Alexa Fluor 488 FACS   0.1 mg Log in to see 10 to 13 Days
$490.19
Details
Mouse Rat Alexa Fluor 700 FACS   0.1 mg Log in to see 10 to 13 Days
$490.19
Details
Mouse Rat Alexa Fluor 647 FACS   0.1 mg Log in to see 10 to 13 Days
$490.19
Details
Mouse Rat Alexa Fluor 750 FACS   0.1 mg Log in to see 10 to 13 Days
$490.19
Details
Mouse Rat Alexa Fluor 594 FACS   0.1 mg Log in to see 10 to 13 Days
$490.19
Details
Mouse Rat Alexa Fluor 350 FACS   0.1 mg Log in to see 10 to 13 Days
$490.19
Details
Mouse Rat Un-conjugated FACS, IP   100 μg Log in to see 11 to 14 Days
$507.83
Details

Siglece Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , ,
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Top referenced anti-Siglece Antibodies

  1. Mouse (Murine) Monoclonal Siglece Primary Antibody for CyTOF, FACS - ABIN4899403 : Wu, Ren, Chen: Siglec-E Negatively Regulates the Activation of TLR4 by Controlling Its Endocytosis. in Journal of immunology (Baltimore, Md. : 1950) 2016 (PubMed)
    Show all 2 Pubmed References

More Antibodies against Siglece Interaction Partners

Mouse (Murine) Sialic Acid Binding Ig-Like Lectin E (Siglece) interaction partners

  1. The Siglec-E-deficient dendritic cells were defective for TRIF (show RNF138 Antibodies)-mediated IFN-beta (show IFNB1 Antibodies) production in response to E. coli infection.

  2. This study demonstrated that virulent parasite Leishmania donovani (AG83+Sias) establish a unique sialic acids-mediated binding and subsequent phagocytosis in the host cell through the selective exploitation of siglec-1 (show SIGLEC1 Antibodies).

  3. new data relating to the structure and function of Siglec-E, the major CD33 (show CD33 Antibodies)-related Siglec expressed on mouse neutrophils, monocytes, macrophages, and dendritic cells.

  4. indicate that Siglec-9 (show SIGLEC9 Antibodies) affects several different signaling pathways in IL-4 (show IL4 Antibodies)-stimulated macrophages, which resulted in enhanced induction of Arg1 (show ARG1 Antibodies) in Siglec-9 (show SIGLEC9 Antibodies)-expressing RAW264 cells

  5. Competitive ELISA assays confirmed the involvement of sulfated (show SULF1 Antibodies) epitopes in the affinity between Siglec-E and cruzipain, probably modified by natural protein environment

  6. Data indicate a role for neuraminidase 1 (Neu1 (show NEU1 Antibodies)) in regulating Siglec E protein-toll-like receptor 4 (TLR4 (show TLR4 Antibodies)) interaction and endotoxemia.

  7. Siglec-E-deficient macrophages showed a propensity toward a tumor-promoting M2 polarization, indicating a secondary role of CD33 (show CD33 Antibodies)-related Siglecs in limiting cancer-promoting inflammation and tumor growth.

  8. siglec-E functions as an inhibitory receptor of neutrophils via positive regulation of NADPH oxidase (show NOX1 Antibodies) activation and ROS (show ROS1 Antibodies) production

  9. These results suggest that sSiglec-9 has an antitumor benefit against MUC1 (show MUC1 Antibodies)-expressing tumor in the transgenic mice.

  10. Siglec-9 (show SIGLEC9 Antibodies) expressed on immune cells may play a role as a potential counterreceptor for MUC1 (show MUC1 Antibodies) and that this signaling may be another MUC1 (show MUC1 Antibodies)-mediated pathway and function in parallel with a growth factor-dependent pathway.

Siglece Antigen Profile

Protein Summary

Putative adhesion molecule that mediates sialic-acid dependent binding to cells. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.

Gene names and symbols associated with Siglece

  • sialic acid binding Ig-like lectin E (Siglece) antibody
  • Cd170 antibody
  • mSiglec-E antibody
  • Siglec5 antibody
  • Siglec9 antibody
  • Siglec12 antibody
  • Siglecl1 antibody

Protein level used designations for Siglece

MIS , SIGLEC-like 1 , myeloid inhibitory siglec , sialic acid binding Ig-like lectin 5 , sialic acid-binding Ig-like lectin 12 , sialic acid-binding Ig-like lectin 5 , sialic acid-binding Ig-like lectin E , sialic acid-binding Ig-like lectin-like 1 , sialic acid-binding immunoglobulin-like lectin E , siglec-12 , siglec-5 , siglec-E , siglec-L1

GENE ID SPECIES
83382 Mus musculus
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