anti-SIRPA Antibodies

Protein Summary

The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternatively spliced transcript variants have been determined for this gene.

Gene names and symbols associated with SIRPA

• signal regulatory protein alpha (SIRPA) antibody
• signal-regulatory protein alpha (SIRPA) antibody
• tyrosine-protein phosphatase non-receptor type substrate 1 (LOC458039) antibody
• tyrosine-protein phosphatase non-receptor type substrate 1 (LOC100400378) antibody
• tyrosine-protein phosphatase non-receptor type substrate 1 (LOC100590224) antibody
• Show all gene names
• signal-regulatory protein alpha (Sirpa) antibody

• AI835480 antibody
• Bit antibody
• CD172a antibody
• MFR antibody
• MYD-1 antibody
• Show all synonym aliases
• P84 antibody
• Ptpns1 antibody
• SHP-1 antibody
• SHPS-1 antibody
• SHPS1 antibody
• SIRP antibody
• SIRP-A1 antibody
• SIRP-B1 antibody
• SIRPA antibody
• swc3 antibody

Protein level used designations for SIRPA

CD172 antigen-like family member A , brain-immunoglobulin-like molecule with tyrosine-based activation motifs , inhibitory receptor SHPS-1 , macrophage fusion receptor , myd-1 antigen , tyrosine phosphatase SHP substrate 1 , tyrosine-protein phosphatase non-receptor type substrate 1 , MyD-1 antigen , SHP substrate 1 , SHPS-1 , protein tyrosine phosphatase, non-receptor type substrate 1 , signal-regulatory protein alpha-1 , sirp-alpha-1 , signal-regulatory protein alpha , signal regulatory protein alpha , tyrosine-protein phosphatase non-receptor type substrate 1-like , brain Ig-like molecule with tyrosine-based activation motifs , brain immunological-like with tyrosine-based motifs , mSIRP-alpha1 , myD-1 antigen , Brain immunoglobulin like protein with tyrosine - based activation motifs , Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1) , Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1) , macrophage membrane protein MFP150 , swine workshop cluster 3 antigen