anti-Synapsin II (SYN2) Antibodies

SYN2 is a member of the synapsin gene family. Additionally we are shipping Synapsin II Proteins (5) and Synapsin II Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SYN2 6854  
SYN2 20965 Q64332
SYN2 29179 Q63537
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Top anti-Synapsin II Antibodies at

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of Synapsin II expression in rat brain extract ( Lane 1), mouse brain extract ( Lane 2) and U87 whole cell lysates ( Lane 3). Synapsin II at 63KD was detected using rabbit anti- Synapsin II Antigen Affinity purified polyclonal antibody (Catalog # ) at 0.5 ??g/mL. The blot was developed using chemiluminescence (ECL) method (Catalog # EK1002). 100 μg 4 to 6 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis SYN2 (Phospho-Ser425) using Jurkat whole cell lysates 100 μL 11 to 12 Days
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of SYN2 using K562 whole  lysates. 100 μL 11 to 12 Days
Human Mouse Un-conjugated ICC, WB dilution: 1 : 1000, sample: synaptic vesicle fraction of rat brain (LP2) Indirect immunolabeling of cultured rat hippocampus neurons (dilution 1 : 500) 100 μg 5 to 6 Days
Human Rabbit Un-conjugated ELISA, WB   100 μL 11 to 13 Days
Human Rabbit Un-conjugated WB Western blot analysis SYN2 (pS425) using Jurkat whole cell lysates. 100 μg 11 to 16 Days
Human Rabbit Un-conjugated ICC, IP, IHC, WB Indirect immunolabeling of cultured rat hippocampus neurons (dilution 1 : 500) Indirect immunolabeling of mouse hippocampus section with anti-synapsin 2 (dilution 1 : 200; red) and mouse anti-synapsin 1 (cat. no. 106 001, dilution 1 : 500; green). Nuclei have been vizualized by DAPI staining. 50 μg 5 to 6 Days
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.22 KDa) . 50 μL 11 to 12 Days
Rat Rabbit Un-conjugated IHC, WB WB on rat brain lysate using Rabbit antibody to rat Synapsin-2 (Syn2, Synapsin 2, Synapsin II): whole serum (ABIN350889) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide abolishes two of the detected bands. IF on 1 day- old mouse cortical cell culture using Rabbit antibody to rat Synapsin-2 (Syn2, Synapsin 2, Synapsin II): whole serum (ABIN350889) at 1: 2000 dilution. DAPI counter stained. 100 μL 7 to 8 Days
Rat Rabbit Un-conjugated WB   100 μL 11 to 16 Days

Top referenced anti-Synapsin II Antibodies

  1. Human Polyclonal SYN2 Primary Antibody for ICC, IP - ABIN1742208 : Chen, Yu, Huang, Yu, Zhu, Lam, Lam, Zhou: Prenatal transfer of polybrominated diphenyl ethers (PBDEs) results in developmental neurotoxicity in zebrafish larvae. in Environmental science & technology 2012 (PubMed)
    Show all 2 Pubmed References

  2. Mouse (Murine) Polyclonal SYN2 Primary Antibody for IP, WB - ABIN266022 : Jovasevic, Corcoran, Leaderbrand, Yamawaki, Guedea, Chen, Shepherd, Radulovic: GABAergic mechanisms regulated by miR-33 encode state-dependent fear. in Nature neuroscience 2015 (PubMed)

  3. Human Monoclonal SYN2 Primary Antibody for ICC, WB - ABIN1742207 : Acuna, Liu, Südhof: How to Make an Active Zone: Unexpected Universal Functional Redundancy between RIMs and RIM-BPs. in Neuron 2016 (PubMed)

More Antibodies against Synapsin II Interaction Partners

Human Synapsin II (SYN2) interaction partners

  1. Our findings support that ASB16-AS1 and SYN2 may represent two novel functional genes underlying bone mineral density variation

  2. These findings contribute to previous work showing dysregulation of Synapsins, particularly SYN2, in mood disorders and improve our understanding of the regulatory mechanisms that precipitate these changes likely leading to the BD or MDD phenotype.

  3. Both GABRA6 and Synapsin II polymorphisms are important risk factors for the development of idiopathic generalized epilepsy in a South Indian population.

  4. Results identify SYN2 as a novel predisposing gene for autism spectrum disorders (ASD) and strengthen the hypothesis that a disturbance of synaptic homeostasis underlies ASD.

  5. Synapsin II is involved in the molecular pathway of lithium treatment in bipolar disorder

  6. SYN2 rs3773364 A>G polymorphism is not a risk factor for susceptibility to epilepsy in this case-control study and meta-analysis.

  7. Results from our study indicate the involvement of SYN2 gene polymorphism in conferring risk to epilepsy; however, the genetic variant does not seem to modulate drug-response in epilepsy pharmacotherapy.

  8. This study suggests a positive association between synapsin II and schizophrenia, implying that synapsin II is involved in the etiology of schizophrenia.

  9. synapsin II variants are associated with susceptibility to schizophrenia.

  10. Syn2 is likely to be involved in the etiology or pathogenesis of schizophrenia.

  11. A case-control study with synapsin II was conducted in 506 bipolar disorder patients and 507 healthy individuals from the Han Chinese population. No association was found in this study.

Mouse (Murine) Synapsin II (SYN2) interaction partners

  1. Synapsin II regulates synaptic transmission and neurite growth in cultured hippocampal neurons.

  2. results reveal a permissive contribution of Syn2 to the expression of normal socio-communicative behavior

  3. These results reveal a new SynII function in the regulation of the time course of GABA release and demonstrate that this function is dependent on the interneuron subtype.

  4. This study demonstrated that synapsin 2 regulating GABA Release from Hippocampal Interneurons.

  5. Pharmacological and knockdown experiments showed that activation of sympathetic neurons by SCFA propionate involves SCFA receptor GPR41 linking to Gbetagamma-PLCbeta3-ERK1/2-synapsin 2

  6. Deletion of synapsin II, a presynaptic protein contributing to epilepsy predisposition in humans, leads to a loss of tonic inhibition in mouse hippocampal slices due to a dramatic decrease in presynaptic asynchronous GABA release.

  7. This study demonostrated that Epileptic synapsin triple knockout mice exhibit progressive long-term aberrant plasticity in the entorhinal cortex.

  8. In synapsin II(-) hippocampal neurons an overexcitable phenotype was observed.

  9. This study demonstrated a seizure-inducing potential of regular handling in both Syn1KO and Syn2KO mice during a period between P21 and 4 1/2 months of age.

  10. Behavioral and neurophysiological features of Syn-2 knockout mice are characterized by observation of the development and progress of seizures from postnatal day 20 to 180.

  11. The histone modification marks were significantly increased in bipolar disorder and major depression and this effect was correlated with significant increases in syn2 gene expression.

  12. Syn II promotes gamma-aminobutyric acid asynchronous release in a Ca(2+)-dependent manner.

  13. Analysis of cultured neurons from wild-type and Syn I,II,III-deficient triple knock-out (TKO) mice shows that synaptic vesicles are severely dispersed in the absence of Syns.

  14. We conclude that neither synapsin I nor synapsin II are directly involved in the regulation of glucose-stimulated insulin secretion and Ca(2)-dependent exocytosis in mouse pancreatic beta-cells.

  15. Synapsin I and II affect distinct excitatory glutamatergic synapses in the hippocampus, synapsin-dependent modulations of synaptic function may use distinct presynaptic response patterns to induce different classes of presynaptic plasticity.[Review]

  16. The supply rate of vesicle trafficking depresses more rapidly in synapsin knock-outs; the phenotype can be fully explained by changing the value of the single parameter in the model that would specify the size of the local reserve pools.

  17. findings suggest that seizure behavior in synapsin I and synapsin II KO mice is not solely determined by cortical activity but rather reflects interplay between cortical activity and activity in other brain regions

  18. Taken together, our results suggest that synapsin II and Rab3a have separate roles in maintaining the total store of synaptic vesicles and cooperate in promoting the latest steps of neuronal secretion.

  19. study provided high sequence coverage information on synapsin 2a and 2b in mouse and rat, revealing highest identity between the species; phosphorylation sites were determined

  20. Results indicate that a cAMP/PKA-dependent mechanism involving the AP-2alpha transcription factor is likely responsible for the increase in neuronal synapsin II following dopamine D1 receptor stimulation or dopamine D2 receptor inhibition.

Synapsin II (SYN2) Antigen Profile

Protein Summary

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family encodes a neuron-specific phosphoprotein that selectively binds to small synaptic vesicles in the presynaptic nerve terminal. The TIMP4 gene is located within an intron of this gene and is transcribed in the opposite direction. Mutations in this gene may be associated with abnormal presynaptic function and schizophrenia. Alternative splicing of this gene results in two transcripts.

Gene names and symbols associated with anti-Synapsin II (SYN2) Antibodies

  • synapsin II L homeolog (syn2.L) antibody
  • synapsin II (SYN2) antibody
  • synapsin IIa (syn2a) antibody
  • synapsin II S homeolog (syn2.S) antibody
  • synapsin-2 (EDI_190690) antibody
  • synapsin II (Syn2) antibody
  • 2900074L19Rik antibody
  • AI836018 antibody
  • AI841723 antibody
  • MGC115109 antibody
  • syn1 antibody
  • SYN2 antibody
  • SYNII antibody
  • SYNIIa antibody
  • SYNIIb antibody
  • zgc:92311 antibody

Protein level used designations for anti-Synapsin II (SYN2) Antibodies

synapsin II , synapsin IIa , synapsin-2 , synapsin2 , synapsin-2-like , synapsin 2

373810 Xenopus laevis
415963 Gallus gallus
436870 Danio rerio
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751980 Taeniopygia guttata
100057285 Equus caballus
100484945 Ailuropoda melanoleuca
100541419 Meleagris gallopavo
5878744 Entamoeba dispar SAW760
6854 Homo sapiens
20965 Mus musculus
29179 Rattus norvegicus
484652 Canis lupus familiaris
782758 Bos taurus
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