anti-TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) Antibodies

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. Additionally we are shipping TAF1 Proteins (10) and TAF1 Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TAF1 270627  
TAF1 317256  
TAF1 6872 P21675
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Top anti-TAF1 Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated ChIP, IHC, WB WB Suggested Anti-TAF1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Daudi cell lysate TAF1 is strongly supported by BioGPS gene expression data to be expressed in Human Daudi cells Human kidney 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated ChIP, WB Quiescent human colon carcinoma HCT116 cultures were treated with 10% FBS for three time points (0, 15, 30min) or (0, 30, 60min) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site. WB Suggested Anti-TAF1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Liver 100 μL Log in to see 2 to 3 Days
$319.00
Details
Human Rabbit Un-conjugated EIA, WB TAF1 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35µg/lane).This demonstrates the TAF1 antibody detected the TAF1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$484.00
Details
Mouse Rabbit Un-conjugated WB TAF1 Antibody (C-term) (ABIN655710) western blot analysis in mouse NIH-3T3 cell line lysates (35 µg/lane). This demonstrates the TAF1 antibody detected the TAF1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using TAF1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB 50 μL Log in to see 2 to 3 Days
$185.00
Details
Human Rabbit Un-conjugated ELISA, WB Immunohistochemistry of rabbit anti-TAF1 antibody. Tissue: prostate. Fixation: formalin fixed paraffin embedded. Antigen retrieval: not required. Primary antibody: Anti-TAF1 at 10 µg/mL for 1 h at RT. Secondary antibody: Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Staining: TAF-1 as precipitated red signal with hematoxylin purple nuclear counterstain. Western blot using  affinity purified anti-TAF1 to detect TAF1 in HeLa nuclear extract (arrowhead). The membrane was probed with the primary antibody at dilutions of 1:100 (lane 1), 1:250 (lane 2), 1: 500 (Lane 3 and 1:1,000 (Lane 4). The identity of the bands at ~95 kDa is unknown, but may be degraded TAF1. Personal Communication, Anne Gegonne, CCR-NCI, Bethesda, MD. 100 μg Log in to see 5 to 7 Days
$598.50
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p) 50 μL Log in to see 11 to 14 Days
$484.00
Details
Chicken Rabbit Un-conjugated IHC, IHC (p), WB 50 μg Log in to see 11 to 14 Days
$551.83
Details
Chicken Rabbit Un-conjugated WB 50 μg Log in to see 11 to 14 Days
$551.83
Details

Top referenced anti-TAF1 Antibodies

  1. Polyclonal TAF1 Primary Antibody for ELISA, WB - ABIN539508 : Solow, Salunek, Ryan, Lieberman: Taf(II) 250 phosphorylates human transcription factor IIA on serine residues important for TBP binding and transcription activity. in The Journal of biological chemistry 2001 (PubMed)
    Show all 3 Pubmed References

More Antibodies against TAF1 Interaction Partners

Fruit Fly (Drosophila melanogaster) TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) interaction partners

  1. TAF1 is involved in both establishing an upper limit of transcription during induction and efficiently turning the gene off once the inducer is removed

  2. results suggest stepwise assembly of a testis-specific TFIID complex (tTFIID) whereby a TAF1 isoform, presumably TAF1-2, is recruited to a core subassembly of tTAFs in spermatocyte nucleoli

  3. TAF1 pre-mRNA elements identified in this study are independently targeted by developmental signaling pathways to result in tissue-specific inclusion of exon 12a and/or 13a.

  4. The existence of a stable coactivator supercomplex consisting of the chromatin-remodeling factor Brahma (SWI/SNF) and the transcription initiation factor TFIID, is shown.

Mouse (Murine) TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) interaction partners

  1. these result suggests that the N-Taf1 gene has an important role in non-dividing neuronal cell rather than in cell division and proliferation during neurogenesis.

  2. Data show that Taf1 is decreased at the osteogenic initiation stage in the maxilla of Tgfbr2 mutant mice.

  3. Appears in pronuclei 6 h post-fertilization and reached a relatively high level before zygotic genome activation.

Human TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1) interaction partners

  1. Our findings highlight the regulatory networks among TFs, lncRNAs, miRNAs, and mRNAs in hepatocellular carcinoma (HCC). Several key molecules, such as hsa-miR-195, lncRNA MALAT1 and TFs TAF1 and HNF4alpha, may contribute to the progression of HCC.

  2. These data directly link sequence variation within the XDP-specific SVA sequence to phenotypic variability in clinical disease manifestation and provide insight into potential mechanisms by which this intronic retroelement may induce transcriptional interference in TAF1 expression.

  3. present a case study where a combination of experimental techniques and computational simulations was used to comprehensively characterize the binding and structure-affinity relationships for a series of Bromosporine-based bivalent bromodomain ligands with a bivalent protein, Transcription Initiation Factor TFIID subunit 1 (TAF1).

  4. The results converge on TAF1 dysfunction in peripheral models of X-linked dystonia-parkinsonism, and provide evidence of altered expression of a canonical gene in this disease. Furthermore, this study illustrates a link between the previously described genetic alterations and TAF1 dysfunction at the transcriptome level.

  5. TAF1 and TAF1L genes harbored not only somatic mutations but also mutational ITH.

  6. N-TAF1 expression is impaired in X-linked dystonia-parkinsonism.

  7. The bromodomains of BRD9, CECR2, and the second bromodomain of TAF1 recognize the longer butyryl mark on histones. In addition, the TAF1 second bromodomain is capable of binding crotonyl marks.

  8. TAF1 variants are associated with dysmorphic features, intellectual disability, and neurological manifestations.

  9. are necessary and sufficient to overcome the barrier of species specificity for human rDNA transcription in mouse cells

  10. TAF1 winged helix domain has intrinsic DNA-binding activity, which depends on characteristic residues that are commonly used by winged helix fold proteins for interacting with DNA.

  11. the surface of the TAF1-TAF7 complex contains two prominent conserved surface pockets, one of which binds selectively to an inhibitory trimethylated histone H3

  12. This study demonistrated that frequencies of polymorphic genotype and allele of TAF1 gene were not different in patients than in control group and that they were not significant for cerebral venous thrombosis.

  13. As cellular ATP levels recover, TAF1 is able to phosphorylate p53 on Thr55, which leads to dissociation of p53 from the p21 promoter.

  14. Lower efficiency of microRNA synthesis directed by TATA box or NF-kappaappaB is a consequence of frequent transcription initiations that lead to RNA polymerase II crowding at pause sites and premature termination.

  15. Although d3-d4 also affect genes potentially related to neurodegenerative processes, their physiologic role as splice variants of TAF1 awaits further exploration

  16. analysis of phosphorylation-dependent regulation of cyclin D1 and cyclin A gene transcription by TFIID subunits TAF1 and TAF7

  17. In the Brazilian population, genetic variations in both uPA and TAFI were not relevant to endometriosis and/or infertility.

  18. TAF7, until now considered only a TFIID component and regulator of TAF1-dependent transcription, also regulates TAF1-independent transcription

  19. 285 patients with autosomal -dominant ataxia were examined, and abnormal or borderline expansions of CAG/CAA within TBP were found.

  20. Results indicate that increased TAF1 expression is associated with progression of human prostate cancers to the lethal castration-resistant state.

TAF1 Antigen Profile

Protein Summary

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is the basal transcription factor TFIID, which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes the largest subunit of TFIID. This subunit binds to core promoter sequences encompassing the transcription start site. It also binds to activators and other transcriptional regulators, and these interactions affect the rate of transcription initiation. This subunit contains two independent protein kinase domains at the N and C-terminals, but also possesses acetyltransferase activity and can act as a ubiquitin-activating/conjugating enzyme. This gene is part of a complex transcriptional unit (TAF1/DYT3), wherein some products share exons with TAF1 as well as additional exons downstream.

Gene names and symbols associated with TAF1

  • TBP-associated factor 1 (Taf1) antibody
  • TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa (TAF1) antibody
  • transcription initiation factor TFIID subunit 1 (LOC5567420) antibody
  • transcription initiation factor TFIID subunit 1 (CpipJ_CPIJ003658) antibody
  • transcription initiation factor TFIID subunit 1 (TAF11.1) antibody
  • transcription initiation factor TFIID, subunit TAF1 (HAF1501) antibody
  • transcription initiation factor TFIID, subunit TAF1 (HAF1502) antibody
  • TATA-box binding protein associated factor 1 (TAF1) antibody
  • transcription initiation factor TFIID subunit 1 (LOC100457071) antibody
  • TATA-box binding protein associated factor 1 (Taf1) antibody
  • 250kDa antibody
  • AU015687 antibody
  • B430306D02Rik antibody
  • BA2R antibody
  • BG:DS00004.13 antibody
  • Ccg-1 antibody
  • CCG1 antibody
  • CCGS antibody
  • cel antibody
  • cell antibody
  • CG17603 antibody
  • d230 antibody
  • Dmel\\CG17603 antibody
  • dmTAF1 antibody
  • dmTAF[[II]]230 antibody
  • dTAF230 antibody
  • dTAF250 antibody
  • dTAFII250 antibody
  • dTAF[[II]]230 antibody
  • dTAF[[II]]250 antibody
  • DYT3 antibody
  • DYT3/TAF1 antibody
  • EfW1 antibody
  • KAT4 antibody
  • l(3)84Ab antibody
  • N-TAF1 antibody
  • NSCL2 antibody
  • OF antibody
  • p230 antibody
  • p250 antibody
  • RGD1562050 antibody
  • SR3-5 antibody
  • TAF antibody
  • TAF(II)250 antibody
  • TAF1 antibody
  • Taf1p antibody
  • TAF2A antibody
  • Taf200 antibody
  • Taf230 antibody
  • Taf250 antibody
  • TAF250/230 antibody
  • TAFII-250 antibody
  • TAFII250 antibody
  • TAF[II]250 antibody
  • TAF[[II]] antibody
  • TAF[[II]]230 antibody
  • Taf[[II]]250 antibody
  • TAF[[II]]250/230 antibody
  • TFIID antibody
  • TFIID TAF250 antibody
  • XDP antibody

Protein level used designations for TAF1

CG17603-PA , CG17603-PB , CG17603-PC , CG17603-PD , CG17603-PE , TATA-associated factor 250 , TBP-associated factor , TBP-associated factor 250 , TBP-associated factor 250kD , TFIID 230 kda subunit , Taf1-PA , Taf1-PB , Taf1-PC , Taf1-PD , Taf1-PE , cell lethal , suppressor of Ras85D 3-5 , TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa , transcription initiation factor TFIID subunit 1 , transcription initiation factor TFIID, subunit TAF1 , TBP-associated factor 1-like , transcription initiation factor TFIID subunit 1-like , TAF(II)250 , TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, neuron specific isoform , TAFII-250 , TBP-associated factor 250 kDa , cell cycle gene 1 protein , cell cycle, G1 phase defect , p250 , transcription initiation factor TFIID 250 kDa subunit , complementation of cell cycle block, G1-to-S , transcription factor TFIID p250 polypeptide , Cell cycle gene 1 protein , Transcription initiation factor TFIID 250 kDa subunit

GENE ID SPECIES
40813 Drosophila melanogaster
736556 Pan troglodytes
5567420 Aedes aegypti
6035208 Culex quinquefasciatus
8250009 Micromonas sp. RCC299
5930833 Physcomitrella patens subsp. patens
5942503 Physcomitrella patens subsp. patens
100348935 Oryctolagus cuniculus
100457071 Pongo abelii
270627 Mus musculus
317256 Rattus norvegicus
6872 Homo sapiens
491950 Canis lupus familiaris
101838159 Mesocricetus auratus
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