TAF1 antibody (Internal Region)

Catalog No. ABIN6265434

Product Details anti-TAF1 Antibody

Target: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))

Binding Specificity: Internal Region

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificity: TAF1 Antibody detects endogenous levels of total TAF1.

Predicted Reactivity: Pig,Bovine,Horse,Rabbit,Dog,Xenopus

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human TAF1, corresponding to a region within the internal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for TAF1

Target: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))

Alternative Name: TAF1 (TAF1 Products)

Synonyms: BG:DS00004.13 antibody, CG17603 antibody, Dmel\\CG17603 antibody, EfW1 antibody, SR3-5 antibody, TAF antibody, TAF1 antibody, TAF200 antibody, TAF230 antibody, TAF250 antibody, TAF250/230 antibody, TAFII-250 antibody, TAFII250 antibody, TAF[II]250 antibody, TAF[[II]] antibody, TAF[[II]]230 antibody, TAF[[II]]250 antibody, TAF[[II]]250/230 antibody, TFIID antibody, TFIID TAF250 antibody, Taf1p antibody, Taf200 antibody, Taf230 antibody, Taf250 antibody, Taf[[II]]250 antibody, cel antibody, cell antibody, d230 antibody, dTAF230 antibody, dTAF250 antibody, dTAFII250 antibody, dTAF[[II]]230 antibody, dTAF[[II]]250 antibody, dmTAF1 antibody, dmTAF[[II]]230 antibody, l(3)84Ab antibody, p230 antibody, 250kDa antibody, AU015687 antibody, B430306D02Rik antibody, Ccg-1 antibody, Ccg1 antibody, KAT4 antibody, N-TAF1 antibody, Taf2a antibody, RGD1562050 antibody, BA2R antibody, CCG1 antibody, CCGS antibody, DYT3 antibody, DYT3/TAF1 antibody, NSCL2 antibody, OF antibody, P250 antibody, TAF2A antibody, XDP antibody, TAF(II)250 antibody, p250 antibody, TBP-associated factor 1 antibody, TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa antibody, transcription initiation factor TFIID subunit 1 antibody, transcription initiation factor TFIID, subunit TAF1 antibody, TATA-box binding protein associated factor 1 antibody, Taf1 antibody, TAF1 antibody, LOC5567420 antibody, CpipJ_CPIJ003658 antibody, TAF11.1 antibody, HAF1501 antibody, HAF1502 antibody, LOC100457071 antibody

Background:

Description: Largest component and core scaffold of the TFIID basal transcription factor complex (PubMed:25412659, PubMed:27007846). Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity (PubMed:25412659). Essential for progression of the G1 phase of the cell cycle (PubMed:11278496, PubMed:15053879, PubMed:2038334, PubMed:8450888, PubMed:8625415, PubMed:9660973, PubMed:9858607). Exhibits histone acetyltransferase activity towards histones H3 and H4 (PubMed:15870300).

Gene: TAF1

Molecular Weight: 212kDa

Gene ID: 6872

UniProt: P21675