TAF1 antibody

Catalog No. ABIN7184220

Product Details anti-TAF1 Antibody

Target: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from internal of Human TAF1.

Isotype: IgG

Application Details

Application Notes: IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for TAF1

Target: TAF1 (TAF1 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 250kDa (TAF1))

Alternative Name: TAF1 (TAF1 Products)

Synonyms: BG:DS00004.13 antibody, CG17603 antibody, Dmel\\CG17603 antibody, EfW1 antibody, SR3-5 antibody, TAF antibody, TAF1 antibody, TAF200 antibody, TAF230 antibody, TAF250 antibody, TAF250/230 antibody, TAFII-250 antibody, TAFII250 antibody, TAF[II]250 antibody, TAF[[II]] antibody, TAF[[II]]230 antibody, TAF[[II]]250 antibody, TAF[[II]]250/230 antibody, TFIID antibody, TFIID TAF250 antibody, Taf1p antibody, Taf200 antibody, Taf230 antibody, Taf250 antibody, Taf[[II]]250 antibody, cel antibody, cell antibody, d230 antibody, dTAF230 antibody, dTAF250 antibody, dTAFII250 antibody, dTAF[[II]]230 antibody, dTAF[[II]]250 antibody, dmTAF1 antibody, dmTAF[[II]]230 antibody, l(3)84Ab antibody, p230 antibody, 250kDa antibody, AU015687 antibody, B430306D02Rik antibody, Ccg-1 antibody, Ccg1 antibody, KAT4 antibody, N-TAF1 antibody, Taf2a antibody, RGD1562050 antibody, BA2R antibody, CCG1 antibody, CCGS antibody, DYT3 antibody, DYT3/TAF1 antibody, NSCL2 antibody, OF antibody, P250 antibody, TAF2A antibody, XDP antibody, TAF(II)250 antibody, p250 antibody, TBP-associated factor 1 antibody, TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa antibody, transcription initiation factor TFIID subunit 1 antibody, transcription initiation factor TFIID, subunit TAF1 antibody, TATA-box binding protein associated factor 1 antibody, Taf1 antibody, TAF1 antibody, LOC5567420 antibody, CpipJ_CPIJ003658 antibody, TAF11.1 antibody, HAF1501 antibody, HAF1502 antibody, LOC100457071 antibody

Background:

Background: Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Exhibits histone acetyltransferase activity towards histones H3 and H4.

Sekiguchi T., Mol. Cell. Biol. 11:3317-3325(1991).
Ruppert S., Nature 362:175-179(1993).
Nolte D., Proc. Natl. Acad. Sci. U.S.A. 100:10347-10352(2003).

Aliases: BA2R antibody, CCG1 antibody, CCGS antibody, Cell cycle G1 phase defect antibody, Cell cycle gene 1 protein antibody, Complementation of cell cycle block G1 to S antibody, DYT3 antibody, N TAF1 antibody, NSCL2 antibody, OF antibody, p250 antibody, TAF 1 antibody, TAF(II)250 antibody, TAF1 antibody, TAF1 RNA polymerase II TATA box binding protein (TBP) associated factor 250 kDa antibody, TAF1_HUMAN antibody, TAF2A antibody, TAFII-250 antibody, TAFII250 antibody, TATA box binding protein (TBP) associated factor RNA polymerase II A 250kD antibody, TBP associated factor 250 kDa antibody, TBP-associated factor 250 kDa antibody, Transcription factor TFIID p250 polypeptide antibody, Transcription initiation factor TFIID 250 kDa subunit antibody, Transcription initiation factor TFIID subunit 1 antibody, XDP antibody

UniProt: P21675