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TIMP3 belongs to the TIMP gene family. Additionally we are shipping TIMP3 Antibodies (191) and TIMP3 Proteins (17) and many more products for this protein.
Showing 10 out of 106 products:
Human TIMP3 ELISA Kit for Sandwich ELISA - ABIN2685673
Tsarouhas, Soufla, Apostolakis, Zaravinos, Panagiotou, Khoury, Hassoulas, Tsatsakis, Spandidos: Transcriptional regulation of TIMPs in ascending aorta aneurysms. in Thrombosis research 2010
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Human TIMP3 ELISA Kit for Sandwich ELISA - ABIN414926
Li, Liang, Tao, Zhou, Li, Chen, Chen: Acidic pH conditions mimicking degenerative intervertebral discs impair the survival and biological behavior of human adipose-derived mesenchymal stem cells. in Experimental biology and medicine (Maywood, N.J.) 2012
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Mouse (Murine) TIMP3 ELISA Kit for Sandwich ELISA - ABIN415606
Shukla, Kumar Shakya, Dhole, Misra: Upregulated expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in BALB/c mouse brain challenged with Japanese encephalitis virus. in Neuroimmunomodulation 2012
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Rat (Rattus) TIMP3 ELISA Kit for Sandwich ELISA - ABIN416332
Kna?, Niczyporuk, Zalewska, Car: The unwounded skin remodeling in animal models of diabetes types 1 and 2. in Physiological research / Academia Scientiarum Bohemoslovaca 2013
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Rat (Rattus) TIMP3 ELISA Kit for Sandwich ELISA - ABIN5525169
Balbaa, El-Zeftawy, Ghareeb, Taha, Mandour: Nigella sativa Relieves the Altered Insulin Receptor Signaling in Streptozotocin-Induced Diabetic Rats Fed with a High-Fat Diet. in Oxidative medicine and cellular longevity 2017
MMP-13 (show MMP13 ELISA Kits) may play a role on physiological turnover of cartilage extracellular matrix and that LRP1 (show LRP1 ELISA Kits) is a key modulator of extracellular levels of MMP-13 (show MMP13 ELISA Kits) and its internalization is independent of the levels of ADAMTS-4 (show ADAMTS4 ELISA Kits), -5 and TIMP-3.
Long noncoding RNA DANCR promotes prostate cancer invasion and metastasis through repressing the expression of TIMP2 (show TIMP2 ELISA Kits)/3
we show that KDM1A (show KDM1A ELISA Kits) promotes cancer metastasis in non-small cell lung cancer cells by repressing TIMP3 (tissue inhibitor of metalloproteinase 3) expression.
Dissecting the interaction between TIMP3 and LRP1 (show LRP1 ELISA Kits) using a synthetic analog of the LRP1 (show LRP1 ELISA Kits) receptor has been reported.
These results implicate TIMP3 as a modulator of cell surface GHR (show GHR ELISA Kits) abundance and the ability of GH to promote cellular signaling.
native glycosaminoglycans interact with TIMP-3.
The expression level of LIPC (show LIPC ELISA Kits), SLC16A8 (show MCT3 ELISA Kits), and TIMP-3 was significantly associated with age-related macular degeneration pathology.
Levels of miR (show MLXIP ELISA Kits)-221/222 are associated negatively with estrogen receptor (show ESR1 ELISA Kits) in in situ tumors and positively with tissue inhibitor of metalloproteinase 3 TIMP3 messenger RNA expression levels in pure invasive breast cancers.
Electrostatic potential calculations suggested a competition between negatively charged GAGs and highly negatively charged complement-like domains of LRP-1 (show LRP1 ELISA Kits) for the binding to a positively charged area of TIMP-3 as an underlying mechanism.
TIMP3 overexpression after myocardial infarction improves myocardial structural remodeling and function by promoting angiogenesis and inhibiting early proteolysis.
Circulating smoke components, including acrolein, contribute to vascular diseases through enhanced MMP-1 (show MMP1 ELISA Kits) and decreased TIMP-3 secretion.
TIMP-3 is downregulated in a distinct subpopulation of atherosclerotic foam cells which have increased MMP-14 (show MMP14 ELISA Kits).
Reactive oxygen species mediate TGF-beta1 (show TGFB1 ELISA Kits)-induced TIMP-3 gene expression
TIMP3 has a role in the pericyte-induced stabilization of newly formed vascular networks that are predisposed to undergo regression and reveal specific molecular targets of the inhibitors regulating these events.
TIMP3 mRNA expression level was upregulated by multidirectional articular motion.
only the N-terminal, but not the C-terminal domain of TIMP-3, results in developmental defects.
metamorphic tail and intestine RNA levels of TIMP-2 (show TIMP2 ELISA Kits), MT1-MMP (show MMP14 ELISA Kits) and Gel-A, but not MT3-MMP (show MMP24 ELISA Kits) or TIMP-3, are elevated during periods of cell death and proliferation
In a clinically relevant CADASIL (show NOTCH3 ELISA Kits) mouse model, we show that exogenous ADAM17 (show ADAM17 ELISA Kits) or HB-EGF (show HBEGF ELISA Kits) restores cerebral arterial tone and blood flow responses, and identify upregulated voltage-dependent potassium channel (show KCNAB2 ELISA Kits) (KV) number in cerebral arterial myocytes as a heretofore-unrecognized downstream effector of TIMP3-induced deficits.
TIMP3 promotes normal microvascular endothelial cell barrier function, at least partially, through inhibition of metalloproteinase-dependent disruption of adherens junctions, and septic downregulation of TIMP3 may contribute to septic MVEC barrier dysfunction.
data strongly suggest that TIMP3 has direct neuroprotective effects that can mitigate the deleterious effects associated with TBI, an area with few if any therapeutic options.
Elevated levels of TIMP3 and vitronectin (show VTN ELISA Kits), acting downstream of Notch3 (show NOTCH3 ELISA Kits)(ECD) deposition, play a role in CADASIL (show NOTCH3 ELISA Kits), producing divergent influences on early CBF (show CEBPZ ELISA Kits) deficits and later white matter lesions.
4-Hydroxyisoleucine improved insulin (show INS ELISA Kits) resistant-like state in 3T3-L1 adipocytes by targeting TACE (show ADAM17 ELISA Kits)/TIMP3 and the insulin (show INS ELISA Kits) signaling pathway.
In a mouse model of prostate cancer, increased tumor growth, proliferation index, increased microvascular density, and invasion was observed in Pten(-/-), Timp3(-/-) prostate tumors compared to Pten(-/-), Timp3(+/+) tumors.
Timp3 status determines p53 (show TP53 ELISA Kits), p38 (show CRK ELISA Kits) and Notch (show NOTCH1 ELISA Kits) coactivation to instruct hepatic cell fate and transformation.
TIMP2 (show TIMP2 ELISA Kits) and TIMP3 play fundamental and differential roles in mediating pathological remodelling, independent from their MMP-inhibitory function
Expansion of stem cells counteracts age-related mammary regression in compound Timp1 (show TIMP1 ELISA Kits)/Timp3-deficient mice.
lack of TIMP3 increases inflammation and polarizes macrophages towards a more inflammatory phenotype resulting in increased atherosclerosis.
These results suggest the crucial role of TIMP-3 in successful implantation and embryo survival and indicate the endometrial stromal decidualization-like in pigs.
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.
metalloproteinase inhibitor 3
, TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory)
, tissue inhibitor metalloproteinase-3
, TIMP metallopeptidase inhibitor 3
, Metalloproteinase inhibitor 3
, MIG-5 protein
, protein MIG-5
, tissue inhibitor of metalloproteinases 3
, tissue inhibitor of metalloproteinase-3
, tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory)
, tissue inhibitor of metalloproteinase 3
, 21 kDa protein of extracellular matrix
, tissue inhibitor of metalloproteinases-3