TIMP Metallopeptidase Inhibitor 4 Proteins (TIMP4)

TIMP4 belongs to the TIMP gene family. Additionally we are shipping TIMP4 Antibodies (206) and TIMP4 Kits (68) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TIMP4 7079 Q99727
TIMP4 110595 Q9JHB3
TIMP4 680130 P81556
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Top TIMP4 Proteins at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Rat His tag 100 μg Log in to see 15 to 18 Days
Escherichia coli (E. coli) Wild boar His tag,GST tag 100 μg Log in to see 15 to 18 Days
Yeast Cow His tag TIMP Metallopeptidase Inhibitor 4 (TIMP4) (AA 30-224), (full length) protein (His tag) 500 μg Log in to see 60 to 71 Days
Baculovirus infected Insect Cells Mouse His tag 50 μg Log in to see 13 to 16 Days
Yeast Human His tag   50 μg Log in to see 8 to 11 Days

TIMP4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
Mouse (Murine) , ,

Rat (Rattus) ,

Top referenced TIMP4 Proteins

  1. Human TIMP4 Protein expressed in Wheat germ - ABIN1322795 : Boström, Wu, Jedrychowski, Korde, Ye, Lo, Rasbach, Boström, Choi, Long, Kajimura, Zingaretti, Vind, Tu, Cinti, Højlund, Gygi, Spiegelman: A PGC1-?-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. in Nature 2012 (PubMed)

More Proteins for TIMP Metallopeptidase Inhibitor 4 (TIMP4) Interaction Partners

Human TIMP Metallopeptidase Inhibitor 4 (TIMP4) interaction partners

  1. MMP2 (show MMP2 Proteins)/TIMP4 ratio is a marker of disease severity and right ventricular function as well as a predictor for survival and time to clinical worsening in idiopathic pulmonary arterial hypertension.

  2. Aspirin-HPR (show HPR Proteins) did not affect the translocation and release of MMPs and TIMP-4 from platelets.

  3. Combining two biomarkers significantly improved discrimination of AHRE (show AHR Proteins). CONCLUSION: TIMP-4, NT-proANP, NT-proBNP were strongest associated with PAF (show PAF Proteins) and AHRE (show AHR Proteins). The discriminatory performance of CHADS2-VASc for PAF (show PAF Proteins) was increased by addition of selected biomarkers.

  4. Our findings provide new evidence that LOX (show LOX Proteins) regulates SNAI2 expression and that SNAI2-mediated TIMP4 secretion plays a role in cancer progression.

  5. This report provides the first example that TIMP-4 regulates carcinogenesis through enriching the tumor progenitor cell population in cervical cancer cells.

  6. Study evaluated MMP-12 (show MMP12 Proteins) and TIMP-1 (show TIMP1 Proteins), TIMP-2 (show TIMP2 Proteins), TIMP-3 (show TIMP3 Proteins), and TIMP-4 levels in 40 patients with asymptomatic and symptomatic critical carotid artery stenosis (CAS (show CSE1L Proteins)) with neurologic symptoms onset within the preceding 12 hours; results suggest that MMP-12 (show MMP12 Proteins) is related to critical CAS (show CSE1L Proteins) independently on symptoms, moreover, TIMP-3 (show TIMP3 Proteins) and TIMP-4 seem to be specifically related to stroke

  7. Concluding, miR (show MLXIP Proteins)-200b-3p mediates regulation of TIMP4 expression in prostate cancer but exact mechanism needs to be investigated.

  8. TIMP1 (show TIMP1 Proteins), TIMP2 (show TIMP2 Proteins), and TIMP4 are increased in aqueous humor from primary open angle glaucoma patients.

  9. ncreased TGFB1 (show TGFB1 Proteins) expression and decreased TIMP-4 expression correlated with atrial fibrosis and extracellular matrix changes in the atria of rheumatic heart disease patients with atrial fibrillation.

  10. Upregulation of plasma TIMP-4 might contribute to PIH [pregnancy-induced hypertension] processes

Mouse (Murine) TIMP Metallopeptidase Inhibitor 4 (TIMP4) interaction partners

  1. there are 7 CpG islands in the TIMP4 promoter which get methylated during the progression of heart failure which leads to its epigenetic silencing.

  2. High fat diet-induced obesity downregulates adipocyte MMP3 (show MMP3 Proteins) expression to trigger adipogenesis, and adipocyte TIMP4 may modulate this process to regulate hyperplastic vs. hypertrophic adipose tissue expansion, fat distribution, and metabolic health in a sex- and depot-dependent manner.

  3. Our findings highlight a protective mechanism induced by PPARgamma (show PPARG Proteins) in deoxycorticosterone acetate-salt treatment, establishing a novel mechanistic link between PPARgamma (show PPARG Proteins) and TIMP-4.

  4. TIMP4 augments contractility and induces differentiation of embryonic stem cells into cardiac phenotype.

  5. TIMP-4 might act as a negative regulator of adipogenesis through NFkB cascade modulation.

  6. Replenishment of myocardial TIMP4 could serve as an effective therapy in post-I/R recovery for patients with reduced TIMP4.

  7. TIMP-4 protein was localized to corpus luteum and theca-intera cells in various periods throughout the pregnancy and postpartum day 1.

  8. Timp4(-/-) mice are more susceptible to MI but not to pressure overload, and TIMP4 functions in its capacity as a metalloproteinase inhibitor after myocardial infarction

  9. Identification of an initiator-like element essential for the expression of the tissue inhibitor of metalloproteinases-4 (Timp-4) gene

  10. molecular cloning and localization of the gene within intron 5 of the synapsin 2 (show SYN2 Proteins) gene

TIMP4 Protein Profile

Protein Summary

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.

Gene names and symbols associated with TIMP4

  • TIMP metallopeptidase inhibitor 4 (TIMP4)
  • TIMP metallopeptidase inhibitor 4, tandem duplicate 3 (timp4.3)
  • tissue inhibitor of metalloproteinase 4 (Timp4)
  • TIMP metallopeptidase inhibitor 4 (Timp4)
  • TIMP-4 protein
  • timp4 protein

Protein level used designations for TIMP4

TIMP metallopeptidase inhibitor 4 , tissue inhibitor of metalloproteinase 4 , TIMP-4 , metalloproteinase inhibitor 4 , tissue inhibitor of metalloproteinases 4 , tissue inhibitor of metalloproteinase , tissue inhibitor of metalloproteinase-4 , TIMP2d

460176 Pan troglodytes
7079 Homo sapiens
317694 Bos taurus
100008691 Oryctolagus cuniculus
100124610 Danio rerio
110595 Mus musculus
680130 Rattus norvegicus
396774 Sus scrofa
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