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TIMP4 belongs to the TIMP gene family. Additionally we are shipping TIMP4 Antibodies (187) and TIMP4 Kits (68) and many more products for this protein.
Showing 10 out of 19 products:
Human TIMP4 Protein expressed in Wheat germ - ABIN1322795
Boström, Wu, Jedrychowski, Korde, Ye, Lo, Rasbach, Boström, Choi, Long, Kajimura, Zingaretti, Vind, Tu, Cinti, Højlund, Gygi, Spiegelman: A PGC1-?-dependent myokine that drives brown-fat-like development of white fat and thermogenesis. in Nature 2012
Combining two biomarkers significantly improved discrimination of AHRE (show AHR Proteins). CONCLUSION: TIMP-4, NT-proANP, NT-proBNP were strongest associated with PAF (show KIAA0101 Proteins) and AHRE (show AHR Proteins). The discriminatory performance of CHADS2-VASc for PAF (show KIAA0101 Proteins) was increased by addition of selected biomarkers.
Our findings provide new evidence that LOX (show LOX Proteins) regulates SNAI2 expression and that SNAI2-mediated TIMP4 secretion plays a role in cancer progression.
This report provides the first example that TIMP-4 regulates carcinogenesis through enriching the tumor progenitor cell population in cervical cancer cells.
Study evaluated MMP-12 (show MMP12 Proteins) and TIMP-1 (show TIMP1 Proteins), TIMP-2 (show TIMP2 Proteins), TIMP-3 (show TIMP3 Proteins), and TIMP-4 levels in 40 patients with asymptomatic and symptomatic critical carotid artery stenosis (CAS (show CSE1L Proteins)) with neurologic symptoms onset within the preceding 12 hours; results suggest that MMP-12 (show MMP12 Proteins) is related to critical CAS (show CSE1L Proteins) independently on symptoms, moreover, TIMP-3 (show TIMP3 Proteins) and TIMP-4 seem to be specifically related to stroke
Concluding, miR (show MLXIP Proteins)-200b-3p mediates regulation of TIMP4 expression in prostate cancer but exact mechanism needs to be investigated.
TIMP1 (show TIMP1 Proteins), TIMP2 (show TIMP2 Proteins), and TIMP4 are increased in aqueous humor from primary open angle glaucoma patients.
ncreased TGFB1 (show TGFB1 Proteins) expression and decreased TIMP-4 expression correlated with atrial fibrosis and extracellular matrix changes in the atria of rheumatic heart disease patients with atrial fibrillation.
Upregulation of plasma TIMP-4 might contribute to PIH [pregnancy-induced hypertension] processes
Expression levels of TIMP-1 (show TIMP1 Proteins), TIMP-3 (show TIMP3 Proteins) and TIMP-4 were negligible (<10% of cells) in primary spontaneous pneumothorax lesions.
No evidence was found for any associations between the TIMP-1,-2,-3, or -4 gene single nucleotide polymorphisms with unexplained recurrent spontaneous abortions in this Han Chinese Han population.
there are 7 CpG islands in the TIMP4 promoter which get methylated during the progression of heart failure which leads to its epigenetic silencing.
High fat diet-induced obesity downregulates adipocyte MMP3 (show MMP3 Proteins) expression to trigger adipogenesis, and adipocyte TIMP4 may modulate this process to regulate hyperplastic vs. hypertrophic adipose tissue expansion, fat distribution, and metabolic health in a sex- and depot-dependent manner.
Our findings highlight a protective mechanism induced by PPARgamma (show PPARG Proteins) in deoxycorticosterone acetate-salt treatment, establishing a novel mechanistic link between PPARgamma (show PPARG Proteins) and TIMP-4.
TIMP4 augments contractility and induces differentiation of embryonic stem cells into cardiac phenotype.
TIMP-4 might act as a negative regulator of adipogenesis through NFkB cascade modulation.
Replenishment of myocardial TIMP4 could serve as an effective therapy in post-I/R recovery for patients with reduced TIMP4.
TIMP-4 protein was localized to corpus luteum and theca-intera cells in various periods throughout the pregnancy and postpartum day 1.
Timp4(-/-) mice are more susceptible to MI but not to pressure overload, and TIMP4 functions in its capacity as a metalloproteinase inhibitor after myocardial infarction
Identification of an initiator-like element essential for the expression of the tissue inhibitor of metalloproteinases-4 (Timp-4) gene
molecular cloning and localization of the gene within intron 5 of the synapsin 2 (show SYN2 Proteins) gene
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. The secreted, netrin domain-containing protein encoded by this gene is involved in regulation of platelet aggregation and recruitment and may play role in hormonal regulation and endometrial tissue remodeling.
TIMP metallopeptidase inhibitor 4
, tissue inhibitor of metalloproteinase 4
, metalloproteinase inhibitor 4
, tissue inhibitor of metalloproteinases 4
, tissue inhibitor of metalloproteinase
, tissue inhibitor of metalloproteinase-4