Protein Summary

The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.

Gene names and symbols associated with TNFAIP6

• TNF alpha induced protein 6 (Tnfaip6) antibody
• TNF alpha induced protein 6 (TNFAIP6) antibody
• tumor necrosis factor alpha induced protein 6 (Tnfaip6) antibody

• Tnfip6 antibody
• TSG-6 antibody
• TSG6 antibody

Protein level used designations for TNFAIP6

tumor necrosis factor alpha induced protein 6 , tumor necrosis factor-inducible gene 6 protein , tumor necrosis factor-inducible protein 6 , TNF alpha-induced protein 6 , TNF-stimulated gene 6 protein , tumor necrosis factor alpha-induced protein 6 , tumor necrosis factor induced protein 6 , tumor necrosis factor, alpha-induced protein 6 , hyaluronate-binding protein , tumor necrosis factor alpha-inducible protein 6 , tumor necrosis factor-stimulated gene-6 protein , TSG-6 , hyaluronate-binding protein PS4 , secreted hyaluronate binding protein