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WFDC2 encodes a protein that is a member of the WFDC domain family. Additionally we are shipping WFDC2 Antibodies (175) and WFDC2 Proteins (27) and many more products for this protein.
Showing 7 out of 26 products:
A panel of three tumor markers CYFRA 21.1, HE4 and ProGRP may play a role for discriminating LC from benign lung disease and subtyping as SCLC.
Serum Smac (show DIABLO ELISA Kits) expression level was significantly lower in the EAOC group than in the control group and benign ovarian tumor group (P< 0.05), while HE4 and CA125 (show MUC16 ELISA Kits) expression levels were significantly higher in the EAOC group than the other two groups.
This study demonstrated that altered expression of HE4 may involve in tumorigenesis in the uterine cervix. Our findings also suggested the presence of a correlation between HE4 expression and the invasive potential of uterine tumors. Therefore it may be thought that the tissue expression of HE4 can be used to differentiate high grade intraepithelial tumors from carcinomas.
High serum HE4 level is associated with epithelial ovarian cancer.
Use of HE4 instead of CA125 (show MUC16 ELISA Kits) did not significantly improve diagnostic performance of risk of malignancy indices 1-4 in patients with an adnexal mass
The significant effect of the normalization of the HE4 marker after therapy and 50% reduction of HE4 levels before interval cytoreductive surgery on PFS and OS confirmed that HE4 might be an independent prognostic factor of treatment response.
HE4 could help with the differentiation of prognostically varied patient groups as well as with the decision-making process associated with the development of individual treatment plans
Studied serum levels of Parkinson's disease-associated protein 7 (DJ-1 (show PARK7 ELISA Kits)) and human epididymis protein 4 (HE4) in endometrial cancer (EC) patients and healthy controls. The median serum concentrations of DJ-1 (show PARK7 ELISA Kits) and HE4 were found to be significantly higher in EC patients compared to controls.
HE4 is a biomarker for ovarian cancer recurrence [review]
Numerous studies indicated that HE4 is able to promote cancer progression and drug resistance. These observations strongly suggest that HE4 may play a significant role in cancer recurrence through its bioactivity in the regulation of malignant behavior at the cellular level. Overall, available data shows that high serum HE4 levels correlate well with ovarian cancer recurrence. [review]
Causal testing implicates Wfdc2 and Hdac3 (show HDAC3 ELISA Kits) as novel genes affecting high density lipoprotein levels
This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.
WAP four-disulfide core domain 2
, WAP four-disulfide core domain 3
, WAP four-disulfide core domain protein 2
, WAP domain containing protein HE4-V4
, epididymal protein 4
, epididymal secretory protein E4
, epididymis-specific, whey-acidic protein type, four-disulfide core
, major epididymis-specific protein E4
, putative protease inhibitor WAP5
, WAP domain-containing protein HE4
, epididymal secretory protein 4
, epididymal protein BE-20