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SPINT2 encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. Additionally we are shipping SPINT2 Antibodies (109) and SPINT2 Kits (10) and many more products for this protein.
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This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. This gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.
hepatocyte growth factor activator inhibitor type 2
, placental bikunin
, serine protease inhibitor, Kunitz type 2
, kunitz-type protease inhibitor 2
, serine protease inhibitor, Kunitz type, 2