SPINT2 Protein (His tag)
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- Target See all SPINT2 Proteins
- SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This SPINT2 protein is labelled with His tag.
- Purpose
- Recombinant Human HAI-2/SPINT2 Protein (His Tag)
- Sequence
- Ala28-Lys197
- Characteristics
- Recombinant Human Hepatocyte Growth Factor Activator Inhibitor Type 2 is produced by our Mammalian expression system and the target gene encoding Ala28-Lys197 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product SPINT2 Protein
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serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2) protein (His tag)
SPINT2 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2) (AA 1-252) protein (GST tag)SPINT2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2) protein (His tag)SPINT2 Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE
serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2) (AA 28-197) protein (His tag)Crystallography grade SPINT2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2) (AA 28-252) protein (rho-1D4 tag)Crystallography grade SPINT2 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2) (AA 28-252) protein (rho-1D4 tag)Crystallography grade SPINT2 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2) protein (Myc-DYKDDDDK Tag)SPINT2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))
- Alternative Name
- HAI-2/SPINT2 (SPINT2 Products)
- Synonyms
- HAI-2 Protein, Pb Protein, DIAR3 Protein, HAI2 Protein, Kop Protein, PB Protein, AL024025 Protein, C76321 Protein, serine peptidase inhibitor, Kunitz type, 2 Protein, serine peptidase inhibitor, Kunitz type 2 Protein, serine protease inhibitor, Kunitz type 2 Protein, Spint2 Protein, SPINT2 Protein
- Background
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Background: Hepatocyte Growth Factor Activator Inhibitor Type 2 (HAI2) is a single-pass type I membrane protein and contains two BPTI/Kunitz inhibitor domains. The first Kunitz domain is mainly responsible for the inhibitory activity against hepatocyte growth factor activator (HGFA). HAI2 is expressed in placenta, kidney, pancreas, prostate, testis, thymus and trachea. HAI2 serves as a inhibitor of HGF activator. It also inhibits plasmin, plasma and tissue kallikrein and factor XIa. Defects in HAI2 are the cause of diarrhea type 3 (DIAR3), also known as congenital sodium diarrhea (CSD).
Synonym: Kunitz-Type Protease Inhibitor 2, Hepatocyte Growth Factor Activator Inhibitor Type 2, HAI-2, Placental Bikunin, SPINT2, HAI2, KOP
- Molecular Weight
- 20.22 kDa
- UniProt
- O43291
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