Piperlongumine
Catalog No. ABIN1027754
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Quick Overview for Piperlongumine (ABIN1027754)
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Purpose
- Apoptosis Inducer
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Characteristics
- Apoptosis inducer in oxidative stressed cells.
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Purity
- >98 %
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Chemical Name
- 1-[(2E)-3-(3,4,5-Trimethoxyphenyl)-2-propenoyl]-5,6-dihydro-2(1H)-pyridinone
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Formula
- C17H19NO5
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Solubility
- Soluble in 25 mg/ml DMSO
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Comment
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Source: Synthetic.
Appearance: Cream Solid -
Restrictions
- For Research Use only
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Format
- Solid
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Precaution of Use
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302
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Handling Advice
- Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302
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Storage
- -20 °C
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Background
- Piperlongumine is a novel compound that exhibits a potential inhibitory effect on washed rabbit platelet aggregation induced by collagen, arachidonic acid and platelet activating factor, without any inhibiting effect on that induced by thrombin. It has recently been found to kill cancer cells by blocking the response that dissipates high oxidative stress and the resulting reactive oxygen species (ROS) generated, meanwhile sparing normal cells.
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Molecular Weight
- 317.3
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CAS-No
- 20069-09-4
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