Forskolin
Catalog No. ABIN1027771
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Quick Overview for Forskolin (ABIN1027771)
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Purpose
- Adenylate cyclase activator
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Characteristics
- Adenylate cyclase activator.
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Purity
- >99 %
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Chemical Name
- (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-6,10,10b-Trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyldodecahydro-1H-benzo[f]chromen-5-yl acetate
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Formula
- C22H34O7
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Solubility
- Soluble to 100 mM in DMSO, and to 10 mM in ethanol
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Comment
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Source: Synthetic.
Appearance: White Solid -
Restrictions
- For Research Use only
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Format
- Solid
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Precaution of Use
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H312 Precautionary Phrases: P280
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Handling Advice
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H312 Precautionary Phrases: P280
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Storage
- -20 °C
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Background
- Forskolin resensitizes cell receptors by activating adenyl cyclase, and increasing the intracellular levels of cAMP. Medically forskolin provides a route to inhibition of colon cancer cell growth and survival. It is also a vasodilator, may be helpful in controlling the cause of glaucoma, reduces urinary tract infections, and may help to increase the skin’s natural resistance to burning under UV light.
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Molecular Weight
- 410.51
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CAS-No
- 66575-29-9
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