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Amifostine

Catalog No. ABIN1027775
$213.75
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Quick Overview for Amifostine (ABIN1027775)

  • Purpose

    HIF-1α activator

    Characteristics

    Cellular protectant.

    Purity

    >98 %

    Chemical Name

    S-{2-[(3-Aminopropyl)amino]ethyl} dihydrogen phosphorothioate

    Formula

    C5H15N2O3PS

    Solubility

    Soluble in water
  • Comment

    Source: Synthetic.
    Appearance: White Solid

    Restrictions

    For Research Use only
  • Format

    Solid

    Precaution of Use

    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302

    Handling Advice

    Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection Hazard Phrases: H302

    Storage

    -20 °C
  • Background

    Amifostine is a cytoprotective adjuvant used in cancer chemotherapy and radiotherapy. Inside cells it detoxifies reactive metabolites of platinum and alkylating agents. Other effects include accelerated DNA repair, induction of cellular hypoxia, inhibition of apoptosis, alteration of gene expression and modification of enzyme activity.

    Molecular Weight

    214.22

    CAS-No

    20537-88-6
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