Andrographolide
Catalog No. ABIN1027785
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Quick Overview for Andrographolide (ABIN1027785)
Application
Apoptosis Induction (AI)
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Purpose
- Apoptosis Inducer
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Characteristics
- Induces mitochondrial -mediated apoptosis in lymphoma cells.
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Purity
- >98 %
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Chemical Name
- (3E)-4-Hydroxy-3-{2-[(1R,4aS,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylenedecahydro-1-naphthalenyl]ethylidene}dihydro-2(3H)-furanone
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Formula
- C20H30O5
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Solubility
- DMSO
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Comment
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Source: Synthetic.
Appearance: Off-white Solid -
Restrictions
- For Research Use only
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Format
- Solid
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Precaution of Use
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
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Handling Advice
- Classification: Caution: Substance not yet fully tested. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
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Storage
- -20 °C
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Background
- Andrographolide is a labdane diterpenoid that is the main bioactive component of the medicinal plant Andrographis paniculata. Is has been shown to be effective against certain cancers, and is an effective purgative. It blocks T-cell proliferation to allogenic stimuli and the chemotactic migration of macrophages induced by complement.
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Molecular Weight
- 350.45
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CAS-No
- 5508-58-7
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