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Anisomycin

Catalog No. ABIN1027873

Quick Overview for Anisomycin (ABIN1027873)

  • Purpose

    p38 MAP kinase activator

    Characteristics

    anoikis sensitizer.

    Purity

    >98 %

    Chemical Name

    (2S,3R,4R)-4-Hydroxy-2-(4-methoxybenzyl)-3-pyrrolidinyl acetate

    Formula

    C14H19NO4

    Solubility

    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Comment

    Source: Synthetic.
    Appearance: White solid

    Restrictions

    For Research Use only
  • Format

    Solid

    Precaution of Use

    Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R23/24/25 - Toxic by inhilation, in contact with skin and if swallowed Hazard Phrases: H301 Precautionary Phrases: P301 + P310

    Handling Advice

    Classification: Toxic. May be harmful or fatal if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible) Risk Phrases: R23/24/25 - Toxic by inhilation, in contact with skin and if swallowed Hazard Phrases: H301 Precautionary Phrases: P301 + P310

    Storage

    -20 °C
  • Background

    Anisomycin is an antibiotic which inhibits protein synthesis. It interferes with protein and DNA synthesis by inhibiting peptidyl transferace on the 80S ribosome system. It can activate stress-activated protein kinases, MAPkinase and other signal transduction pathways.

    Molecular Weight

    265.31

    CAS-No

    22862-76-6
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