Garcinol
1 image
Catalog No. ABIN1439973
$134.31
Plus shipping costs $50.00
Shipping to:
United States
Delivery in 2 to 3 Business Days
Quick Overview for Garcinol (ABIN1439973)
Application
Blocking Antibody (Inhibition)
-
-
Characteristics
-
Potent histone acetyltransferases inhibitor
Induces HeLa cell apoptosis
Anti-inflammatory and anti-carcinogenic
-
-
-
-
Restrictions
- For Research Use only
-
-
-
Storage
- 4 °C
-
-
-
Background
- Garcinol is an inhibitor of the histone acetyltransferases (HATs) p300 and PCAF with IC50 of 7 and 5 uM, respectively. It also inhibits the HAT GCN5 in Cryptococcus neoformans, inducing temperature sensitivity and impairing growth. A polyisoprenylated benzophenone isolated from Garcinia indica, garcinol promotes neurogenesis and ex vivo expansion of human hematopoietic stem cells. It induces apoptosis in several types of cancer cells and has anti-inflammatory actions.
-
CAS-No
- 78824-30-3
-
-
You are here:
