alpha-conotoxin GI (alpha conotoxin GI)

Catalog No. ABIN1540039

Quick Overview for alpha-conotoxin GI (alpha conotoxin GI) (ABIN1540039)

Target: alpha-conotoxin GI

Application: Blocking Reagent (BR)

Product Details

Purpose: alpha-conotoxin G blocks nAChR receptors

Sequence: Glu-Cys2-Cys3-Asn-Pro-Ala-Cys7-Gly-Arg-His-Tyr-Ser-Cys13-NH2Disulfide bonds between Cys2-Cys7, Cys3-Cys13

Application Details

Restrictions: For Research Use only

Handling

Target Details

Target: alpha-conotoxin GI

Background: Alpha-conotoxin GI has been isolated from the venom of the cone snail Conus geographus. This conotoxin acts on postsynaptic membranes, which bind to the nicotinic acetylcholine receptor (nAChR). It Inhibits nAChR currents. The highestaffinity site for Cis the alpha/delta site on mouse muscle-derived BC3H-1 receptor, and the other site (alpha/gamma site) on nicotinic receptors from Torpedo californica electric organ.

Molecular Weight: 1437.61 Da

CAS-No: 76862-65-2