BPDP (BML-278)
Quick Overview for BPDP (BML-278) (ABIN1884296)
-
-
Characteristics
-
Off white Powder
Molecular formula: C24H25NO4
-
-
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Soluble to 5 mg/mL in DMSO
-
Storage
- RT
-
-
-
Background
-
Synonyms:
BML-278, N-Benzyl-3,5-dicarbethoxy-4-phenyl-1,4-dihydropyridine
Sirt activator based on a dihydropyridine structural scaffold. EC150 (effective concentration able to increase enzyme activity by 150 %) is 1 µM for Sirt1, 25 µM for Sirt2, and 50 µM for Sirt3. The compound is active in whole cells and arrests cell cycle at G1/S phase in U937 cells. -
Molecular Weight
- 391.5 Da
-
-