Browse our anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) Antibodies

Cow (Bovine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

1. Differential expression of CD25 (show IL2RA Antibodies) and IDO mRNA with high and low virulence bovine viral diarrhea virus might reflect temporal differences in transcription during the immune response elicited by these viral strains.

2. IDO may be involved in downregulating immune responses to M. avium subsp. paratuberculosis and other virulent mycobacteria, which may be an example of the pathogen harnessing host immunoregulatory pathways to aid survival.

3. INDO participates in IFN-gama-induced death of bovine luteal cells, through a mechanism that involves degradation of tryptophan, thereby reducing tryptophan concentrations to a point insufficient to meet luteal cells needs

Rhesus Monkey Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

1. SIV-infected macaques exhibiting progression to AIDS displayed greater expression of TGF-beta (show TGFB1 Antibodies) and indoleamine 2,3 dioxygenase in CD8 (show CD8A Antibodies)+ T cells from mesentric lymph nodes.

Human Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

1. this data we have identified the structure of two possible compounds that may be even more potent pharmacological repressors of IDO-1.

2. Prognostic value of IDO in acute myeloid leukemia (show BCL11A Antibodies).

3. These findings indicate that IDO1 has the potential to participate in or contribute to the formation of new capillaries, supporting the applicability of IDO1-targeting molecular therapy in lung cancer.

4. induces PD-L1 (show CD274 Antibodies) expression by melanoma cells

5. PD-L1 (show CD274 Antibodies), IDO-1, and B7-H4 (show VTCN1 Antibodies) are differentially expressed in human lung carcinomas and show limited co-expression. While PD-L1 (show CD274 Antibodies) and IDO-1 are associated with increased tumor-infiltrating lymphoycte and IFN-gamma (show IFNG Antibodies) stimulation, B7-H4 (show VTCN1 Antibodies) is not.

6. Data show that indole 23-dioxygenase (IDO) is variably expressed by tumor-infiltrating immune cells or reactive cells rather than lymphoma cells in diffuse large-cell lymphoma (DLBCL).

7. High IDO1 expression is associated with hepatocellular carcinoma.

8. Epacadostat significantly decreases Treg proliferation induced by IDO production from IFN-gamma (show IFNG Antibodies) plus LPS (show IRF6 Antibodies) matured human DCs, although the Treg phenotype does not change

9. Inhibition of TOR (show RORC Antibodies) serine-threonine kinases (mTOR (show FRAP1 Antibodies)) strongly induced indoleamine 23-dioxygenase 1 (IDO1) expression and activity, corroborating its ability to recruit Treg cells in the tumor microenvironment.

10. MALAT1-overexpressed MSCs promoted M2 macrophage polarization and this effect was mediated by MALAT1-induced IDO expression, suggesting that MALAT1 may enhance the immunosuppressive properties of MSCs in vivo.

Mouse (Murine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

1. Data suggest that Indoleamine 2,3-dioxygenase 1 (IDO1) appears to be a potential hallmark of liver lesions, and its deficiency protects mice from CCl4 (show CCL4 Antibodies)-induced fibrosis mediated by Th17 cells down-regulation and tryptophan 2,3-dioxygenase (TDO (show TDO2 Antibodies)) compensatory increase.

2. Findings suggest non-redundant neurophysiological roles for indoleamine 2,3-dioxygenase 1, indoleamine 2,3-dioxygenase 2 (show IDO2 Antibodies) and tryptophan 2,3-dioxygenase (show TDO2 Antibodies) in modulating brain activities and metabolism.

3. These results show IDO is upregulated with RSV infection and this upregulation likely participates with IFN-gamma (show IFNG Antibodies) in inhibition of virus replication and suppression of some host cell responses to infection.

4. Lipopolysaccharide (LPS (show TLR4 Antibodies)) stimulation increased the expression and activity of the immunoregulatory enzyme IDO1 in hepatic stellate cells (HSCs), and LPS (show TLR4 Antibodies)/HSCs stimulated aryl hydrocarbon receptor (AhR (show AHR Antibodies)) signaling in cocultured regulatory T cells.

5. this study shows that the presence of IFN-alpha (show IFNA Antibodies) at antigen sensitization activates an IDO1/TGF-beta (show TGFB1 Antibodies)-dependent anti-inflammatory program that upon antigenic rechallenge prevents inflammation via plasmacytoid dendritic cells

6. Across strains, networks depicted a predominance of genes under-expressed in microglia relative to macrophages that may be a precursor for the different response of both cell types to challenges. The detected transcriptome differences enhance the understanding of the role of IDO1 in the microglia transcriptome under unchallenged conditions.

7. Data show that indoleamine 23-dioxygenase 1 (IDO-1) inhibitors 1-methyl-D-tryptophan was able to alleviate most of the behavioural changes resulting from unpredictable chronic mild stress (UCMS) exposure.

8. IDO did not play a pivotal role in the suppression of allergic airway inflammation through adipose-derived stem cells, suggesting that it is not the major regulator responsible for suppressing allergic airway inflammation.

9. These results indicate that Platelet-activating Factor -mediated endotoxin tolerance is initiated via IDO- and JAK (show JAK3 Antibodies)/STAT (show STAT1 Antibodies)-dependent expression of SOCS3 (show SOCS3 Antibodies).

10. Aortic Plasmacytoid dendritic cells expressed CCR9 (show CCR9 Antibodies) and indoleamine 2,3-dioxygenase 1 (IDO-1), an enzyme involved in driving the generation of regulatory T cells (Tregs).

Pig (Porcine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners