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IDO1 Products

(Indoleamine 2,3-Dioxygenase 1 (IDO1))

Categories

This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011].

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Featured IDO1 Categories

IDO1 Antibodies

High quality antibodies with extensive validation data.

IDO1 ELISA Kits

Reliable ELISA kits for a wide range of species.

IDO1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended IDO1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
  • (4)
Cat. No. ABIN185488
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, ELISA, IHC, FACS
Validations
  • (1)
  • (4)
Cat. No. ABIN1043819
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (5)
Cat. No. ABIN517166
Quantity 100 μg
Datasheet Datasheet

Recommended IDO1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6975449
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (5)
  • (1)
Cat. No. ABIN6974104
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6967580
Quantity 96 tests
Datasheet Datasheet

Recommended IDO1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123419
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1307387
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7320560
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our IDO1 products

Kozuma, Takada, Toyokawa, Kohashi, Shimokawa, Hirai, Tagawa, Okamoto, Oda, Maehara: "Indoleamine 2,3-dioxygenase 1 and programmed cell death-ligand 1 co-expression correlates with aggressive features in lung adenocarcinoma." in: European journal of cancer (Oxford, England : 1990), Vol. 101, pp. 20-29, (2019) (PubMed).

Ilic, Gruden-Movsesijan, Cvetkovic, Tomic, Vucevic, Aranzamendi, Colic, Pinelli, Sofronic-Milosavljevic: "Trichinella spiralis Excretory-Secretory Products Induce Tolerogenic Properties in Human Dendritic Cells via Toll-Like Receptors 2 and 4." in: Frontiers in immunology, Vol. 9, pp. 11, (2019) (PubMed).

Abomaray, Gidlöf, Götherström: "Mesenchymal Stromal Cells Are More Immunosuppressive In Vitro If They Are Derived from Endometriotic Lesions than from Eutopic Endometrium." in: Stem cells international, Vol. 2017, pp. 3215962, (2018) (PubMed).

Matheus, Simão, Amaral, Brito, Malta, Matos, Santana, Rodrigues, Albejante, Bach, Dalboni, Camacho, Dellê: "Indoleamine 2, 3-dioxygenase (IDO) increases during renal fibrogenesis and its inhibition potentiates TGF-β 1-induced epithelial to mesenchymal transition." in: BMC nephrology, Vol. 18, Issue 1, pp. 287, (2017) (PubMed).

Ishiguro, Watanabe, Nakamura, Yamamura, Ando, Goto, Hirooka: "S100G expression and function in fibroblasts on colitis induction." in: International immunopharmacology, Vol. 39, pp. 92-96, (2017) (PubMed).

Lam, Li, Tipoe, Youdim, Fung: "Monoamine oxidase A upregulated by chronic intermittent hypoxia activates indoleamine 2,3-dioxygenase and neurodegeneration." in: PLoS ONE, Vol. 12, Issue 6, pp. e0177940, (2017) (PubMed).

Jiang, Zhao, Lin, Hu, Che, Li, Wang, Xu, Zhang, Peng: "Expression of indoleamine 2,3-dioxygenase in a murine model of Aspergillus fumigatus keratitis." in: International journal of ophthalmology, Vol. 9, Issue 4, pp. 491-6, (2016) (PubMed).

Chimal-Ramírez, Espinoza-Sánchez, Chávez-Sánchez, Arriaga-Pizano, Fuentes-Pananá: "Monocyte Differentiation towards Protumor Activity Does Not Correlate with M1 or M2 Phenotypes." in: Journal of immunology research, Vol. 2016, pp. 6031486, (2016) (PubMed).

Wei, Mei, Tang, Liu, Li, Li, Zhu: "1-Methyl-tryptophan attenuates regulatory T cells differentiation due to the inhibition of estrogen-IDO1-MRC2 axis in endometriosis." in: Cell death & disease, Vol. 7, Issue 12, pp. e2489, (2016) (PubMed).

Jiang, Li, Liu, Sun, Cui, Wu, Gao: "Indoleamine 2,3-dioxygenase is upregulated in the brain of rats with acute pancreatitis." in: Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], Vol. 15, Issue 3, pp. 281-5, (2016) (PubMed).

Synonyms and alternative names related to IDO1

indoleamine 2,3-dioxygenase 1 (IDO1), indoleamine 2,3-dioxygenase 1 L homeolog (ido1.L), indoleamine 2,3-dioxygenase 1 (ido1), indoleamine 2,3-dioxygenase 1 (Ido1), indoleamine 2,3-dioxygenase 1-like (LOC100050681), cd107b, ido, IDO, Ido, IDO-1, IDO1, INDO, indo, Indo

Protein level used designations for IDO1

  • indoleamine-pyrrole 2,3 dioxygenase
  • indoleamine 2,3-dioxygenase 2
  • proto-IDO
  • putative indoleamine 2,3-dioxygenase
  • indoleamine 2,3-dioxygenase 1
  • indolamine 2,3 dioxygenase
  • indole 2,3-dioxygenase
  • indoleamine-pyrrole 2,3-dioxygenase
  • IDO-1
  • indoleamine 23-dioxygenase
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