Browse our anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) Antibodies

Full name:: anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) Antibodies (ITGAX)

On www.antibodies-online.com are 647 Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) Antibodies from 33 different suppliers available. Additionally we are shipping Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) Proteins (7) and and many more products for this protein. A total of 658 Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) products are currently listed.

Synonyms:: AI449405, Cd11c, Cr4, N418, RGD1561123, SLEB6

list all antibodies	Gene Name	GeneID	UniProt
	ITGAX	3687	P20702
	ITGAX	499271
	ITGAX	16411	Q9QXH4
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Top referenced anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) Antibodies

Mouse (Murine) Monoclonal ITGAX Primary Antibody for IHC (f), IHC (fro) - ABIN2688918 : Gao, Liu, Wen, Zhang, Durbin, Liu, Zheng: Differentiation of monocytic cell clones into CD8 alpha+ dendritic cells (DC) suggests that monocytes can be direct precursors for both CD8 alpha+ and CD8 alpha- DC in the mouse. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
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Mouse (Murine) Monoclonal ITGAX Primary Antibody for CyTOF, FACS - ABIN4289490 : Gheryani, Coffelt, Gartland, Rumney, Kiss-Toth, Lewis, Tozer, Greaves, Dear, Miller: Generation of a novel mouse model for the inducible depletion of macrophages in vivo. in Genesis (New York, N.Y. : 2000) 2013 (PubMed)
Show all 5 Pubmed References
Human Monoclonal ITGAX Primary Antibody for CyTOF, FACS - ABIN4900698 : Zhang, Wang, Liu, Sun, Ding, Fu, Min, Zhu, Cao: Effective induction of immune tolerance by portal venous infusion with IL-10 gene-modified immature dendritic cells leading to prolongation of allograft survival. in Journal of molecular medicine (Berlin, Germany) 2004 (PubMed)
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Mouse (Murine) Monoclonal ITGAX Primary Antibody for FACS - ABIN2688921 : Huleatt, Lefrançois: Antigen-driven induction of CD11c on intestinal intraepithelial lymphocytes and CD8+ T cells in vivo. in Journal of immunology (Baltimore, Md. : 1950) 1995 (PubMed)
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Human Monoclonal ITGAX Primary Antibody for FACS, IHC (f) - ABIN302039 : Bullard, Hu, Adams, Schoeb, Barnum: p150/95 (CD11c/CD18) expression is required for the development of experimental autoimmune encephalomyelitis. in The American journal of pathology 2007 (PubMed)
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Human Monoclonal ITGAX Primary Antibody for FACS, IHC (f) - ABIN302060 : Sadhu, Ting, Lipsky, Hensley, Garcia-Martinez, Simon, Staunton: CD11c/CD18: novel ligands and a role in delayed-type hypersensitivity. in Journal of leukocyte biology 2007 (PubMed)
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Human Monoclonal ITGAX Primary Antibody for FACS, IHC (f) - ABIN302018 : Gang, Choi, Lee, Nham: Identification of critical residues for plasminogen binding by the alphaX I-domain of the beta2 integrin, alphaXbeta2. in Molecules and cells 2007 (PubMed)
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Mouse (Murine) Monoclonal ITGAX Primary Antibody for CyTOF, FACS - ABIN4900697 : Yin, Zhao, Zhang, Zhang: Impact of CD200-Fc on dendritic cells in lupus-prone NZB/WF1 mice. in Scientific reports 2016 (PubMed)
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Human Monoclonal ITGAX Primary Antibody for FACS, IHC (f) - ABIN301988 : Vorup-Jensen, Chi, Gjelstrup, Jensen, Jewett, Xie, Shimaoka, Linhardt, Springer: Binding between the integrin alphaXbeta2 (CD11c/CD18) and heparin. in The Journal of biological chemistry 2007 (PubMed)
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Human Monoclonal ITGAX Primary Antibody for FACS, IHC (f) - ABIN302095 : Angel, Lala, Chen, Edgar, Ostrovsky, Dunbar: CD14+ antigen-presenting cells in human dermis are less mature than their CD1a+ counterparts. in International immunology 2007 (PubMed)
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More Antibodies against Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) Interaction Partners

Human Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) interaction partners

This study provides evidence that CD11c is involved in the susceptibility to Behcet's disease in a Chinese Han population.
The main mechanism of Integrin alphaXbeta2 I-domain binding to RAGE is a charge interaction, in which the acidic moieties of Integrin alphaXbeta2 I-domains, including E244, and D249, recognize the basic residues on the RAGE V-domain encompassing K39, K43, K44, R104, and K107.
Studies indicate that CD11c+ T-bet+ memory B cells exhibit a distinct transcriptome.
Studies indicate enriched expression of TBX21 (T-bet), which is important for B cell survival and response to antigen, was observed in CD11c+ B cells.
CD11c, expressed not only in Hairy cell leukemia but also in dendritic cells, macrophages and monocytes is a differentiation marker for inflammation. Prolonged inflammation in the microenvironment of CLL cells may cause a susceptibility to autoimmune disorders and secondary tumors in CLL, in this way, an increase in mortality.
We can achieve possible clinical significance of lymphoma tumor microenvironments through CD11c and FOXP3 (show FOXP3 Antibodies) immunohistochemistry stains in extranodal diffuse large B-cell lymphoma patients receiving R-CHOP (show DDIT3 Antibodies) therapy.
Circulating CD11c+ T cells were associated with the expression of multiple adhesion molecules in women, suggesting that these cells have high tissue homing potential. These data suggest that CD11c expression distinguishes a population of circulating T cells during bacterial infection with innate capacity and mucosal homing potential.
CD8 (show CD8A Antibodies)+ T cells of Behcet's disease patients exhibited increased CD11c expression levels, which may contribute to disease pathogenesis.
High expression of CD11c decreased the risk of death and relapse, and may be regarded as an alternative indicator of favorable prognosis in patients with gastric cancer.
the CD11c molecule possesses four different cellular patterns in the periprosthetic tissues.

Mouse (Murine) Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) interaction partners

CD11c and its partner Itgb2 (show ITGB2 Antibodies) were required for DC capture of CD47 (show CD47 Antibodies)-deficient cells. CD11b (show ITGAM Antibodies) was not necessary for this process but could partially compensate in the absence of CD11c. Mice with DCs lacking Talin1, Itgb2 (show ITGB2 Antibodies), or CD11c were defective in supporting T-cell proliferation and differentiation induced by CD47 (show CD47 Antibodies)-deficient cell associated antigen.
Deleting IL-2 in CD11c(high)MHCII(+) cells induces spontaneous colitis resembling human inflammatory bowel disease.
Accumulation of lung CD11c+ DCs is significantly higher in both inflammatory and fibrotic phases of the disease but that percentages got reduced in the absence of TGF-beta (show TGFB1 Antibodies).
The findings of this study indicate that radio-resistant cells, expressing CD11c-GFP+ and located in the CNS, irrespective of their origin, which might be the yolk sac (show ADCY10 Antibodies) or the periphery, show a phenotype capable of antigen presentation under neuroinflammatory conditions following induction of EAE.
These data demonstrated that the CD11c+ lamina propria mononuclear phagocytes from this postinfectious irritable bowel syndrome mouse model were not only able to transfer enteric inflammation to the normal mice but also caused abnormal intestinal function, characterized by epithelial barrier disruption and visceral hyperalgesia.
the CD11c promoter was unexpectedly active and triggered Mgat2 (show MGAT2 Antibodies) deletion within multiple hematopoietic lineages, showed remarkably poor penetrance within native DC populations, and produced almost undetectable levels of green fluorescent protein signal. These findings show that the CD11c promoter is not DC-specific, and extreme care should be taken in the interpretation of data using any mouse created using the CD11c-CRE
Studies indicate that the autoimmune phenotype in DEF6 and SWAP-70 knock-out (DKO) mice is characterized by the accumulation of B cell subset that expresses high levels of CD11c and T-bet (ABCs).
MyD88 (show MYD88 Antibodies) signaling in lysozyme (show LYZ Antibodies) M and CD11c-expressing myeloid cells, as well as in pulmonary epithelial cells, is critical to restore inflammatory cytokine and antimicrobial peptide (show CAMP Antibodies) production, leading to efficient neutrophil recruitment and enhanced bacterial clearance.
Results implicate a monocytic origin of CD11c(+) cells in inflamed islets and suggest that therapeutic regulatory T cells directly or indirectly regulate their influx by altering the chemotactic milieu in the islets.
this study shows that PU.1 functions as a positive regulator of CD11c gene expression by directly binding to the Itgax promoter and through transactivation of the Irf4 (show IRF4 Antibodies) gene

Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) Antigen Profile

Antigen Summary

This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.

Alternative names and synonyms associated with Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX)

integrin subunit alpha X (ITGAX) antibody
integrin subunit alpha X (Itgax) antibody
integrin alpha X (Itgax) antibody

AI449405 antibody
Cd11c antibody
Cr4 antibody
N418 antibody
RGD1561123 antibody
SLEB6 antibody

Protein level used designations for ITGAX

CD11 antigen-like family member C , integrin alpha-X , integrin, alpha X (antigen CD11C (p150), alpha polypeptide) , leu M5, alpha subunit , leukocyte adhesion glycoprotein p150,95 alpha chain , leukocyte adhesion receptor p150,95 , leukocyte surface antigen p150,95, alpha subunit , myeloid membrane antigen, alpha subunit , p150 95 integrin alpha chain , CD11C (p150) alpha polypeptide , complement receptor 4 , integrin aX

GENE ID	SPECIES
3687	Homo sapiens
499271	Rattus norvegicus
16411	Mus musculus

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Show all anti-Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) Antibodies with Pubmed References

Human Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) interaction partners

Mouse (Murine) Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX) interaction partners

Antigen Summary

Alternative names and synonyms associated with Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX)

Protein level used designations for ITGAX