anti-PYCARD Antibodies

Protein Summary

This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm\; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with PYCARD

• PYD and CARD domain containing (PYCARD) antibody
• PYD and CARD domain containing (Pycard) antibody
• PYD and CARD domain containing (pycard) antibody

• 9130417A21Rik antibody
• Asc antibody
• asc1 antibody
• CARD5 antibody
• masc antibody
• Show all synonym aliases
• TMS antibody
• TMS-1 antibody
• TMS1 antibody
• TNS1 antibody
• zAsc antibody
• zgc:109874 antibody

Protein level used designations for PYCARD

apoptosis-associated speck-like protein containing a CARD , caspase recruitment domain-containing protein 5 , target of methylation-induced silencing 1 , PYD and CARD domain-containing protein