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AFF3 Products

(AF4/FMR2 Family, Member 3 (AFF3))

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This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured AFF3 Categories

AFF3 Antibodies

High quality antibodies with extensive validation data.

Recommended AFF3 Antibodies

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Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Dog, Human, Mouse, Pig, Rabbit, Rat
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Cat. No. ABIN2778345
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
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Cat. No. ABIN2780415
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
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Cat. No. ABIN6742449
Quantity 100 μL
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Recommended AFF3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
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Cat. No. ABIN3088769
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
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Cat. No. ABIN3134385
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our AFF3 products

To, Faseruk, Gokgoz, Pinnaduwage, Done, Andrulis: "LAF-4 is aberrantly expressed in human breast cancer." in: International journal of cancer. Journal international du cancer, Vol. 115, Issue 4, pp. 568-74, (2005) (PubMed).

Hiwatari, Taki, Taketani, Taniwaki, Sugita, Okuya, Eguchi, Ida, Hayashi: "Fusion of an AF4-related gene, LAF4, to MLL in childhood acute lymphoblastic leukemia with t(2;11)(q11;q23)." in: Oncogene, Vol. 22, Issue 18, pp. 2851-5, (2003) (PubMed).

von Bergh, Beverloo, Rombout, van Wering, van Weel, Beverstock, Kluin, Slater, Schuuring: "LAF4, an AF4-related gene, is fused to MLL in infant acute lymphoblastic leukemia." in: Genes, chromosomes & cancer, Vol. 35, Issue 1, pp. 92-6, (2002) (PubMed).

Synonyms and alternative names related to AFF3

AF4/FMR2 family member 3 (AFF3), AF4/FMR2 family, member 3 (aff3), AF4/FMR2 family, member 3 (Aff3), 3222402O04Rik, A730046J16, id:ibd5053, LAF-4, LAF4, Laf4, MLLT2-like

Protein level used designations for AFF3

  • AF4/FMR2 family, member 3
  • si:dkey-19j7.2
  • AF4/FMR2 family member 3
  • MLLT2-related protein
  • lymphoid nuclear protein 4
  • lymphoid nuclear protein related to AF4
  • protein LAF-4
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