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AES Products

(Amino-terminal Enhancer of Split (AES))

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The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured AES Categories

AES Antibodies

High quality antibodies with extensive validation data.

AES ELISA Kits

Reliable ELISA kits for a wide range of species.

AES Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AES Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, FM, WB
Validations
  • (3)
Cat. No. ABIN6656093
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, FM, WB
Validations
  • (3)
Cat. No. ABIN6655675
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application EIA, IF, WB
Validations
  • (3)
Cat. No. ABIN499225
Quantity 0.1 mg
Datasheet Datasheet

Recommended AES ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1121505
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN1121503
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1121504
Quantity 96 tests
Datasheet Datasheet

Recommended AES Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3120816
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3088588
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1344513
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our AES products

Han, Gorman, Singh, Chi: "Repression of HNF1α-mediated transcription by amino-terminal enhancer of split (AES)." in: Biochemical and biophysical research communications, Vol. 468, Issue 1-2, pp. 14-20, (2015) (PubMed).

Sarma, Yaseen: "Amino-terminal enhancer of split (AES) interacts with the oncoprotein NUP98-HOXA9 and enhances its transforming ability." in: The Journal of biological chemistry, Vol. 286, Issue 45, pp. 38989-9001, (2011) (PubMed).

Martin, Vuori: "Regulation of Bcl-2 proteins during anoikis and amorphosis." in: Biochimica et biophysica acta, Vol. 1692, Issue 2-3, pp. 145-57, (2004) (PubMed).

Jan, Matter, Pai, Chen, Pilch, Komatsu, Ong, Fukuda, Ruoslahti: "A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors." in: Cell, Vol. 116, Issue 5, pp. 751-62, (2004) (PubMed).

Tsao, Lodish, Fruebis: "ACRP30, a new hormone controlling fat and glucose metabolism." in: European journal of pharmacology, Vol. 440, Issue 2-3, pp. 213-21, (2002) (PubMed).

Chen, Courey: "Groucho/TLE family proteins and transcriptional repression." in: Gene, Vol. 249, Issue 1-2, pp. 1-16, (2000) (PubMed).

Synonyms and alternative names related to AES

amino-terminal enhancer of split (AES), amino-terminal enhancer of split (Aes), amino-terminal enhancer of split (aes), amino-terminal enhancer of split S homeolog (aes.S), AES, AES-1, aes-1, AES-2, aes-2, AL024115, ESP1, Esp1, esp1, GRG, Grg, grg, Grg-5, GRG5, Grg5, grg5, TLE5, Tle5, tle5, xgrg-5, zgc:64216

Protein level used designations for AES

  • gp130-associated protein GAM
  • related to Drosophila groucho
  • R-esp1
  • amino enhancer of split
  • amino enhancer split
  • amino-terminal enhancer of split
  • transducin-like enhancer of split 4 homolog of Drosophila E(spl)
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