Browse our PRKAG3 Proteins (PRKAG3)

The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.

• protein kinase AMP-activated non-catalytic subunit gamma 3 (Prkag3)
• protein kinase AMP-activated non-catalytic subunit gamma 3 (PRKAG3)
• protein kinase, AMP-activated, gamma 3 non-catalytic subunit S homeolog (prkag3.S)
• protein kinase, AMP-activated, gamma 3 non-catatlytic subunit b (prkag3-b)
• protein kinase, AMP-activated, gamma 3 non-catatlytic subunit (Prkag3)

• Amkg3 protein
• AMPKG3 protein
• AMPKg3L protein
• AMPKg3S protein
• PRKAG3 protein
• Show all synonym aliases
• prkag3-a protein

5'-AMP-activated protein kinase subunit gamma-3 , AMP-activated protein kinase gamma 3 subunit , protein kinase, AMP-activated, gamma 3 non-catatlytic subunit , 5'-AMP-activated protein kinase gamma-3 non-catalytic subunit long form , AMP-activated protein kinase gamma subunit , protein kinase non-catalytic gamma subunit , AMP-activated protein kinase, non-catalytic gamma-3 subunit , AMP-activated protein kinase gamma 3 , AMPK-activated protein kinase gamma-3 subunit , protein kinase, AMP-activated, gamma 3 non-catalytic subunit a , protein kinase, AMP-activated, gamma 3 non-catalytic subunit , AMP-activated protein kinase subunit gamma , 5'-AMP-activated protein kinase subunit gamma-3-like , 5'-AMP-activated protein kinase, gamma-3 subunit , AMPK gamma-3 chain , AMPK gamma3 , AMPK subunit gamma-3 , 5'-AMP-activated protein kinase gamma-3 subunit , AMP-activated protein kinase gamma