RCAN1 antibody (Internal Region)

Catalog No. ABIN1019651

The Goat Polyclonal anti-RCAN1 antibody has been validated for WB and ELISA. It is suitable to detect RCAN1 in samples from Mouse.

Quick Overview for RCAN1 antibody (Internal Region) (ABIN1019651)

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Reactivity: Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This RCAN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Grade: Verified

Product Details anti-RCAN1 Antibody

Binding Specificity: Internal Region

Purpose: Calcipressin-1

Sequence: HIGSSHLAPP NPD

Specificity: This antibody is expected to recognize all three reported isoforms (NP_004405.3, NP_981962.1, NP_981963.1).

Cross-Reactivity: Cow, Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-HIGSSHLAPPNPD, from the internal region of the protein sequence according to NP_004405.3, NP_981962.1, NP_981963.1.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Approx 40 kDa band corresponding to isoform 1L observed in Mouse Brain lysates and this band is not present in the KO mouse. Additional bands around 55 kDa were consistently observed, however these band were also observed in the KO mice and

Peptide ELISA: antibody detection limit dilution 1:32000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for RCAN1

Target: RCAN1 (Regulator of Calcineurin 1 (RCAN1))

Alternative Name: RCAN1

Background: RCAN1, regulator of calcineurin 1, ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1, Down syndrome candidate region 1, Down syndrome critical region gene 1, OTTHUMP00000108621, OTTHUMP00000108622, OTTHUMP00000214669, OTTHUMP00000214670, calcipressin-1, calcium and

Gene ID: 1827, 54720, 266766

NCBI Accession: NP_004405, NP_981962, NP_981963

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development