HDAC1 antibody (AA 467-482)

Catalog No. ABIN1042601

The Mouse Monoclonal anti-HDAC1 antibody has been validated for WB, IF, ICC, IP, FACS, IHC (p) and ChIP. It is suitable to detect HDAC1 in samples from Human, Mouse and Rat. There is 1 publication available.

Quick Overview for HDAC1 antibody (AA 467-482) (ABIN1042601)

Target: HDAC1 (Histone Deacetylase 1 (HDAC1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This HDAC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Chromatin Immunoprecipitation (ChIP)

Clone: 1-00E-003

Product Details anti-HDAC1 Antibody

Binding Specificity: AA 467-482

Sequence: EEKPEAKGVK EEVKLA

Purification: Protein G

Immunogen: Synthetic peptide: EEKPEAKGVKEEVKLA, corresponding to C terminal amino acids 467-482 of Human and mouse HDAC1

Isotype: IgG1

Application Details

Application Notes: Optimal antibody dilution should be determined by titration, however as a guideline try, WB: 1/500 - 1/4000. Detects a band of approximately 57 kDa (predicted molecular weight: 55 kDa).

Comment:

Myeloma, fusion partners: X63-Ag8.653

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified antibody (from supernatant) containing PBS + 0.1 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

References for anti-HDAC1 antibody (ABIN1042601)

Lagger, OCarroll, Rembold, Khier, Tischler, Weitzer, Schuettengruber, Hauser, Brunmeir, Jenuwein, Seiser: "Essential function of histone deacetylase 1 in proliferation control and CDK inhibitor repression." in: The EMBO journal, Vol. 21, Issue 11, pp. 2672-81, (2002) (PubMed).

Target Details for HDAC1

Target: HDAC1 (Histone Deacetylase 1 (HDAC1))

Alternative Name: HDAC1 

Background: Synonyms:
DKFZp686H12203 antibody,GON 10 antibody,HD 1 antibody,HD1 antibody,HDAC 1 antibody,HDAC1 antibody,hdac1: histone deacetylase 1 antibody,HDAC1_HUMAN antibody,Histone deacetylase 1 (HD1) antibody

Gene ID: 3065, 433759, 297893

OMIM: 601241

UniProt: Q13547, O09106

Pathways: Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Mitotic G1-G1/S Phases, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Negative Regulation of intrinsic apoptotic Signaling, Embryonic Body Morphogenesis