Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (N-Term) antibody

Details for Product No. ABIN1077401
Target
Binding Specificity
N-Term
15
7
7
4
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse, Rat
93
32
22
Host
Rabbit
67
22
7
2
Clonality
Polyclonal
Conjugate
Un-conjugated
11
10
10
5
4
4
3
2
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (IF), ELISA, Western Blotting (WB)
49
40
35
26
9
4
4
4
2
1
1
Options
Immunogen Rabbit polyclonal TDGF1 antibody was raised against a 17 amino acid peptide near the amino terminus of human TDGF1.
Blocking Peptide Blocking peptide for this product available: ABIN1383497
Isotype IgG
Purification Affinity chromatography purified via peptide column
Target
Alternative Name TDGF1 (TDGF1 Antibody Abstract)
Background Teratocarcinoma-derived growth factor 1 (TDGF1 or Cripto) is a member of the epidermal growth factor-cripto FRL1 cryptic protein family and is involved in the activation of several different signaling pathways during embryonic development and cellular transformation. It is first expressed in the forming mesoderm during gastrulation but later in development the expression is restricted to the truncus arteriosus of the developing heart. This suggests that TDGF1 mediates the progression of epiblastic cells that give rise to the mesoderm. TDGF1 overexpression is characteristic of human gastric and colorectal carcinomas.
Synonyms: Teratocarcinomaderived growth factor 1, Epidermal growth factor-like cripto protein CR1, Cripto-1 growth factor, CRGF, CR, CRGF, CRIPTO, Cripto-1
Molecular Weight 21 kDa
Gene ID 6997
NCBI Accession NP_003203
Pathways EGFR Signaling Pathway
Application Notes TDGF1 antibody can be used for detection of TDGF1 by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.
Comment

(NT) Teratocarcinomaderived growth factor 1

Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS containing 0.02 % Sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage 4 °C
Storage Comment TDGF1 antibody can be stored at 4 °C for three months. At -20 °C stable for up to one year.
Expiry Date 12 months
Images
Image no. 1 for anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (N-Term) antibody (ABIN1077401) anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (N-Term) antibody (Image 1)
Image no. 2 for anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (N-Term) antibody (ABIN1077401) anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (N-Term) antibody (Image 2)