Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (N-Term) antibody

Details for Product No. ABIN357430
Target
Binding Specificity
N-Term
15
7
7
4
2
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
90
33
23
Host
Rabbit
64
22
7
2
Clonality
Polyclonal
Conjugate
Un-conjugated
10
9
9
5
4
4
3
2
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
47
37
32
26
8
4
4
3
2
2
1
Options
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human TDGF1.
Isotype Ig Fraction
Specificity This antibody detects CRIPTO (TDGF1) at N-term.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Target
Alternative Name TDGF1 / CRIPTO (TDGF1 Antibody Abstract)
Background TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers. This protein could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. It is preferentially expressed in gastric and colorectal carcinomas compared to their normal counterparts.Synonyms: CRGF, Cripto-1 growth factor, Epidermal growth factor-like cripto protein CR1, Teratocarcinoma-derived growth factor 1
Molecular Weight 21168 Da
Gene ID 6997, 9606
UniProt P13385
Pathways EGFR Signaling Pathway
Application Notes ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Images
Image no. 1 for anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (N-Term) antibody (ABIN357430) anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (N-Term) antibody (Image 1)
Image no. 2 for anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (N-Term) antibody (ABIN357430) anti-Teratocarcinoma-Derived Growth Factor 1 (TDGF1) (N-Term) antibody (Image 2)