Spectrin beta Chain, Erythrocyte (SPTB) antibody

Catalog No. ABIN108438

The Mouse Monoclonal anti-Spectrin beta Chain, Erythrocyte antibody (Clone DB2) (ABIN108438) specifically detects Spectrin beta Chain, Erythrocyte in WB, IHC and IP. The antibody is reactive with Human samples.

Quick Overview for Spectrin beta Chain, Erythrocyte (SPTB) antibody (ABIN108438)

Target: Spectrin beta Chain, Erythrocyte (SPTB)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: DB2

Product Details

Specificity: The antibody is specific to the 220kD human erythroid b-spectrin. The protein is also present in the membranes of human skeletal muscle cells

Immunogen: Monoclonal antibody to erythroid b-spectrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells. Ghost proteins of human red blood cells were used as immunogen

Isotype: IgG1

Application Details

Application Notes: Various immunochemical reactions to detect erythroid spectrins. Identification of erythroid leukemias. Can be used also to monitor the integrity of muscle cell plasma membranes. Works in immunoprecipitation, western blotting and immunocytochemistry. No re

Restrictions: For Research Use only

Handling

Storage: 4 °C

Target Details

Target: Spectrin beta Chain, Erythrocyte (SPTB)

Alternative Name: Erythroid beta Spectrin

Background: Monoclonal Antibody to Human Spectrins

Pathways: Regulation of Actin Filament Polymerization