CD5 antibody (AA 27-233)

Catalog No. ABIN1098109

Product Details anti-CD5 Antibody

Target: CD5

Binding Specificity: AA 27-233

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD5 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA

Purpose: CD5 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CD5 (AA: 27-233) expressed in E. Coli.

Clone: 6A11

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CD5 antibody (ABIN1098109)

Youinou, Renaudineau: "CD5 expression in B cells from patients with systemic lupus erythematosus." in: Critical reviews in immunology, Vol. 31, Issue 1, pp. 31-42, (2011) (PubMed).

de Wit, Souwer, van Beelen, de Groot, Muller, Klaasse Bos, Jorritsma, Kapsenberg, de Jong, van Ham: "CD5 costimulation induces stable Th17 development by promoting IL-23R expression and sustained STAT3 activation." in: Blood, Vol. 118, Issue 23, pp. 6107-14, (2011) (PubMed).

Target Details for CD5

Target: CD5

Alternative Name: CD5 (CD5 Products)

Background: The human cd5 gene has two alternative exons 1: exon 1A (E1A) which encodes the full-length (FL) CD5 protein and exon 1B (E1B) which encodes a truncated (TR) isoform. The FL variant of CD5 protein is translocated to the plasma membrane, while its TR variant is retained in the cytoplasm.

Molecular Weight: 54.6 kDa

Gene ID: 921

UniProt: P06127