FZD5 antibody (AA 151-217)

Catalog No. ABIN1098119

Product Details anti-FZD5 Antibody

Target: FZD5 (Frizzled Family Receptor 5 (FZD5))

Binding Specificity: AA 151-217

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FZD5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: FZD5 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human FZD5 (AA:151-217) expressed in E. Coli.

Clone: 2D12

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-FZD5 antibody (ABIN1098119)

Terabayashi, Funato, Fukuda, Miki: "A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5)." in: The Journal of biological chemistry, Vol. 284, Issue 39, pp. 26716-24, (2009) (PubMed).

Katoh, Katoh et al.: "Conserved POU-binding site linked to SP1-binding site within FZD5 promoter: Transcriptional mechanisms of FZD5 in undifferentiated human ES cells, fetal liver/spleen, adult colon, pancreatic islet, ..." in: International journal of oncology, Vol. 30, Issue 3, pp. 751-5, (2007) (PubMed).

Target Details for FZD5

Target: FZD5 (Frizzled Family Receptor 5 (FZD5))

Alternative Name: FZD5 (FZD5 Products)

Background: Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD5 protein is believed to be the receptor for the Wnt5A ligand.

Molecular Weight: 64.5 kDa

Gene ID: 7855

UniProt: Q13467

Pathways: WNT Signaling