FOXP1 antibody (AA 481-677)

Catalog No. ABIN1098120

This anti-FOXP1 antibody is a Mouse Monoclonal antibody detecting FOXP1 in WB, ELISA, IHC and FACS. Suitable for Human. This Primary Antibody has been cited in 2+ publications.

Quick Overview for FOXP1 antibody (AA 481-677) (ABIN1098120)

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 6E4

Product Details anti-FOXP1 Antibody

Binding Specificity: AA 481-677

Purpose: FOXP1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human FOXP1 (AA: 481-677) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-FOXP1 antibody (ABIN1098120)

Chen, Xiao, Zhang, Li, Liu, Zhao, Ma, Luo, Qiu, Huang, Korteweg, Gu: "Transcription factors E2A, FOXO1 and FOXP1 regulate recombination activating gene expression in cancer cells." in: PLoS ONE, Vol. 6, Issue 5, pp. e20475, (2011) (PubMed).

Jones, Bhattacharyya, Simkus, Vallieres, Veenstra, Zhou: "The RAG1 V(D)J recombinase/ubiquitin ligase promotes ubiquitylation of acetylated, phosphorylated histone 3.3." in: Immunology letters, Vol. 136, Issue 2, pp. 156-62, (2011) (PubMed).

Target Details for FOXP1

Target: FOXP1 (Forkhead Box P1 (FOXP1))

Alternative Name: FOXP1

Background: This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.

Molecular Weight: 75.3 kDa

UniProt: Q9H334

Pathways: Chromatin Binding, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response