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NEFH antibody (AA 968-1020)

NEFH Reactivity: Human IHC, ELISA Host: Mouse Monoclonal 8H10 unconjugated
Catalog No. ABIN1098127
  • Target See all NEFH Antibodies
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    Binding Specificity
    • 15
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 968-1020
    Reactivity
    • 107
    • 77
    • 61
    • 47
    • 29
    • 23
    • 12
    • 12
    • 9
    • 9
    • 9
    • 6
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 65
    • 53
    • 7
    Mouse
    Clonality
    • 80
    • 45
    Monoclonal
    Conjugate
    • 77
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEFH antibody is un-conjugated
    Application
    • 77
    • 40
    • 37
    • 26
    • 22
    • 20
    • 18
    • 13
    • 13
    • 12
    • 11
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
    Purpose
    NEFH Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human NEFH (AA: 968-1020) expressed in E. Coli.
    Clone
    8H10
    Isotype
    IgG1
    Top Product
    Discover our top product NEFH Primary Antibody
  • Application Notes
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Singh, Yan, Hull, Read, OSullivan, Henderson, Rose, Greer, McCombe: "Levels of phosphorylated axonal neurofilament subunit H (pNfH) are increased in acute ischemic stroke." in: Journal of the neurological sciences, Vol. 304, Issue 1-2, pp. 117-21, (2011) (PubMed).

    Sellner, Patel, Dassan, Brown, Petzold: "Hyperacute detection of neurofilament heavy chain in serum following stroke: a transient sign." in: Neurochemical research, Vol. 36, Issue 12, pp. 2287-91, (2011) (PubMed).

  • Target
    NEFH (Neurofilament, Heavy Polypeptide (NEFH))
    Alternative Name
    NEFH (NEFH Products)
    Background
    Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

    Molecular Weight
    112.4 kDa
    Gene ID
    4744
    UniProt
    P12036
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