Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) antibody

Catalog No. ABIN1098196

This Mouse Monoclonal antibody specifically detects in IHC, WB and IF/ICC. It exhibits reactivity toward Mouse.

Quick Overview for Cav3.1 Ca2+ Channel (AA 2052-2172), (C-Term) antibody (ABIN1098196)

Target: Cav3.1 Ca2+ Channel

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (fixed cells) (IF/ICC)

Clone: S178A-9

Product Details

Binding Specificity: AA 2052-2172, C-Term

Purpose: Anti-Cav3.1 Ca+2 Channel Mouse Monoclonal Antibody

Specificity: This antibody recognizes human, mouse, and rat Cav3.1. It does not cross-react with Cav3.2.

Cross-Reactivity: Human, Mouse, Rat

Cross-Reactivity (Details): No cross Reactivity with Cav3.2

Purification: Purified by Protein G affinity chromatography.

Immunogen: Fusion protein corresponding to aa 2052-2172 (cytoplasmic C-terminus) of mouse Cav3.1 (accession no. NP_001106284.1).

Isotype: IgG1

Application Details

Application Notes: Immunoblotting: use at 1-2 μg/mL. A band of >200 kDa is detected.
Immunohistochemistry: use at 1-10 μg/mL.
These are recommended concentrations. User should determine optimal concentrations for their application.
Positive control: Rat brain membranes.

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: Dilute in PBS or medium which is identical to that used in the assay system.

Concentration: Lot specific

Buffer: PBS, pH 7.4, 50 % glycerol, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: This antibody is stable for at least one (1) year at -20°C.

Target Details

Target: Cav3.1 Ca2+ Channel

Alternative Name: Cav3.1 Ca+2 Channel

Background: Voltage-dependent T-type calcium channel subunit α,Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient. Cav3.1 is a low-voltage- activated T-type calcium channel expressed throughout the body. Drugs that block T-type calcium channels are used as antihypertensives and antiepileptics and possibly in some anesthetics and antipsychotics.

NCBI Accession: NP_001106284

UniProt: Q9WUT2