RIPK2 antibody (AA 11-30)

Catalog No. ABIN1104002

The Rabbit Polyclonal anti-RIPK2 antibody has been validated for WB and ICC. It is suitable to detect RIPK2 in samples from Human, Mouse and Rat.

Quick Overview for RIPK2 antibody (AA 11-30) (ABIN1104002)

Target: RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIPK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Product Details anti-RIPK2 Antibody

Binding Specificity: AA 11-30

Specificity: Recognizes full-length RICK (60  kDa). Positive control: A431 or K562 cell lysate.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide corresponding to aa 11-30 at the N-terminus of human RICK

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: ICC ( - 1:10, 10 μg/mL), WB ( - 1, 1 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C, stable for 1 year. Avoid freeze-thaw cycles.

Target Details for RIPK2

Target: RIPK2 (Receptor-Interacting Serine-threonine Kinase 2 (RIPK2))

Alternative Name: RICK / RIP2 / CCK

Background: Name/Gene ID: RIPK2
Subfamily: RIP
Family: Protein Kinase

Synonyms: RIPK2, CARD-carrying kinase, CARDIAK, Growth-inhibiting gene 30, Receptor interacting protein 2, Receptor-interacting protein 2, Rick Kinase, RIP2, RICK, RIP-2, Tyrosine-protein kinase RIPK2, CARD3, GIG30

Gene ID: 8767

UniProt: O43353

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Toll-Like Receptors Cascades