SDF1 beta antibody

Catalog No. ABIN110541

This anti-SDF1 beta antibody is a Rabbit Polyclonal antibody detecting SDF1 beta in WB, IP and IHC. Suitable for Rat.

Quick Overview for SDF1 beta antibody (ABIN110541)

Target: SDF1 beta (SDF1b) (Stromal Cell Derived Factor 1 beta (SDF1b))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDF1 beta antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Product Details anti-SDF1 beta Antibody

Specificity: Cross-reactivity to SDF-1b of other species has not been determined

Immunogen: This polyclonal antibody, which reacts with both mouse and rat SDF-1b, was generated using E. coli-expressed mouse SDF-1b as an immunogen.

Isotype: IgG

Application Details

Application Notes: The tested titer for Western blot is 1:1,000, immunoprecipitation, 1:300-500; and immunohistochemistry, 1:100-500.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 1mg/ml

Storage: 4 °C

Target Details for SDF1 beta

Target: SDF1 beta (SDF1b) (Stromal Cell Derived Factor 1 beta (SDF1b))

Alternative Name: SDF-1 beta (Stromal Cell-Derived Factor, PBSF)

Background: SDF-1ß (stromal cell-derived factor-ß )1, also known as pre-B-cell growth-stimulating factor (PBSF)2, is a 74-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line1. Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis in mice3. SDF-1 has been shown to be chemotactic for lymphocytes4. In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells5,6., SDF-1 binding to CXCR4 inhibits HIV-1 entry5,6.

UniProt: P48061