C1S antibody (activated)

Catalog No. ABIN1105613

The Mouse Monoclonal anti-C1S antibody has been validated for WB, IP, IHC (p), IHC (fro), EIA and Func. It is suitable to detect C1S in samples from Human.

Quick Overview for C1S antibody (activated) (ABIN1105613)

Target: C1S (Complement Component 1, S Subcomponent (C1S))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This C1S antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Functional Studies (Func)

Clone: M241

Product Details anti-C1S Antibody

Binding Specificity: activated

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein G

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % bovine serum albumin

Storage: 4 °C

Storage Comment: Store at 2 - 8 °C.

Target Details for C1S

Target: C1S (Complement Component 1, S Subcomponent (C1S))

Alternative Name: C1s

Background: C protein activated C1s is a subcomponent of the first component of C (C1). Activated C1s is a glycosylated single-polypeptide zymogen of 85 kD. Activation of the proenzyme C1s occurs through cleavage by the active form of C1r. The activated protease, activated C1s, consists of a disulfide-linked H chain and a L chain. Activated C1s is a serine protease and its catalytic site is located in the L chain. Activation of the classical C pathway is triggered by activated C1s which cleaves C4 and C2 to form the C3 convertase, C4bC2a.Synonyms: C1 esterase, Complement 1s, Complement C1s, Complement C1s subcomponent, Complement component 1 subcomponent s

Gene ID: 9606

UniProt: P09871

Pathways: Complement System