CD147 antibody

Catalog No. ABIN1105886

The Mouse Monoclonal anti-CD147 antibody is suitable to detect CD147 in samples from Human. It has been validated for IHC (fro).

Quick Overview for CD147 antibody (ABIN1105886)

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD147 antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: CB43

Product Details anti-CD147 Antibody

Specificity: CB43 recognizes the antigen CD147. This antigen is a single chain type I transmembrane with a MW of 50-60 kDa. It has been described as a tumor-cell-derived soluble factor that stimulates expression of collagenases by fibroblasts.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Purified

Immunogen: Native leucocytes. A BALB/c mouse was immunized. After three weeks the mouse was boosted and the splenocytes fused with myeloma cell line NSO. A positive hybridoma obtained after three limiting dilutions served as source for the hybridoma.

Isotype: IgM

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for CD147

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Alternative Name: CD147

Background: Synonyms: 5F7, BSG, Basigin, Collagenase stimulatory factor, EMMPRIN, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, OK blood group antigen, TCSF, Tumor cell-derived collagenase stimulatory factor

Gene ID: 682

NCBI Accession: NP_001719

UniProt: P35613

Pathways: S100 Proteins