Gai2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide-2) antibody
The Rabbit Polyclonal anti-Gai2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide-2) antibody (ABIN110589) specifically detects Gai2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide-2) in IP and WB.
The antibody is reactive with Human samples.
1 image
Catalog No. ABIN110589
$214.50
Plus shipping costs $50.00
0.2 mg
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United States
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Quick Overview for Gai2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide-2) antibody (ABIN110589)
Target
Gai2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide-2)
Reactivity
Human
Host
Rabbit
Clonality
Polyclonal
Application
Immunoprecipitation (IP), Western Blotting (WB)
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Storage
- 4 °C
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- Gai2 (Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide-2)
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Background
- Gai2 is a 40-41 kDa alpha-subunit of heterotrimeric protein, that shares sequence homology with Gai3 and Gai1. All these G proteins can be ADP-ribosylated at the carboxy terminal Cys of the CAAX sequence, interfering with receptor coupling. Gai2 is expressed widely in tissues and cell lines. Activation of PLC-ß by Gai-coupled receptors is the result of release of Gß. subunits from Gai. Gai2regulates potassium channel activation. Mutation at Arg179 has been identified in tumors. This and the Q205L mutant inhibit adenylyl cyclase.
Target
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