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DC-SIGN/CD209 antibody

CD209 Reactivity: Human FACS, IF Host: Mouse Monoclonal UW60-1 unconjugated

Catalog No. ABIN1106050

Datasheet as PDF

Target See all DC-SIGN/CD209 (CD209) Antibodies

DC-SIGN/CD209 (CD209) (CD209)
Reactivity
96

27

22

1

1
Human
Host
70

39

4

1
Mouse
Compatible Secondaries
Clonality
69

45
Monoclonal
Conjugate
58

8

8

5

5

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This DC-SIGN/CD209 antibody is un-conjugated
Application
67

45

31

28

24

13

7

7

6

3

3

3

2

2

1

1
Flow Cytometry (FACS), Immunofluorescence (IF)

Specificity

The mouse monoclonal antibody UW60.1 recognizes CD209 (DC-SIGN), a 44 kDa transmembrane receptor expressed on the surface of dendritic cells and macrophages.

Cross-Reactivity (Details)

Species reactivity (tested):Human

Purification

Protein-A affinity chromatography

Purity

> 95 % pure (by SDS-PAGE)

Immunogen

CD209-His-tagged fusion protein

Clone

UW60-1

Isotype

IgG1

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anti-CD209 (CD209) antibody
CD209 Reactivity: Human WB, FACS, IHC, IF, ISt, StM Host: Mouse Monoclonal C209-1781 unconjugated

anti-CD209 (CD209) antibody
CD209 Reactivity: Human FACS, IHC, IP, IHC (p) Host: Rat Monoclonal h209 unconjugated

anti-CD209 (CD209) (AA 1-404) antibody
CD209 Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated

anti-CD209 (CD209) antibody
CD209 Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated

anti-CD209 (CD209) (AA 115-238) antibody
CD209 Reactivity: Mouse WB, IHC, ICC Host: Rabbit Polyclonal unconjugated

anti-CD209 (CD209) antibody
CD209 Reactivity: Human FACS, IHC, ICC Host: Mouse Monoclonal UW60-1 unconjugated

anti-CD209 (CD209) antibody
CD209 Reactivity: Human WB, FACS, IHC, IF, ISt, StM Host: Mouse Monoclonal rC209-1781 unconjugated Recombinant Antibody

anti-CD209 (CD209) (AA 271-380) antibody
CD209 Reactivity: Human IF, ELISA, IP Host: Mouse Monoclonal 3B10 unconjugated

Application Notes

Optimal working dilution should be determined by the investigator.

Restrictions

For Research Use only
Concentration

1.0 mg/mL

Buffer

PBS, approx. pH 7.4, 15 mM sodium azide

Preservative

Sodium azide

Precaution of Use

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice

Avoid repeated freezing and thawing.

Storage

4 °C/-20 °C

Storage Comment

Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Target

DC-SIGN/CD209 (CD209) (CD209)

Alternative Name

CD209 / DC-SIGN (CD209 Products)

Background

CD209, also known as DC-SIGN (dendritic cell-specific ICAM-3-grabbing nonintegrin) is a transmembrane receptor expressed on the surface of dendritic cells and macrophages, which recognizes numerous pathogens ranging from parasites to viruses. Its N-terminal domain is transmembrane, whereas a tandem-repeat neck domain and the C terminal C-type lectin carbohydrate recognition domain have dual function as a pathogen recognition receptor and a cell adhesion receptor. The neck region is responsible for homo-oligomerization which allows the receptor to bind multivalent ligands with high avidity. A ligand of CD209 is also CD50 (ICAM-3).Synonyms: C-type lectin domain family 4 member L, CLEC4L, DC-SIGN1, DCSIGN, DCSIGN1, Dendritic Cell Marker, Dendritic cell-specific ICAM-3-grabbing non-integrin 1

Gene ID

9606

UniProt

Q9NNX6