CD28 antibody

Catalog No. ABIN1106181

This anti-CD28 antibody is a Mouse Monoclonal antibody detecting CD28 in FACS, Func and IHC (fro). Suitable for Human.

Quick Overview for CD28 antibody (ABIN1106181)

Target: CD28

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD28 antibody is un-conjugated

Application: Flow Cytometry (FACS), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: B-T3

Product Details anti-CD28 Antibody

Specificity: This antibody recognises the B7/BB1 receptor (B7/BB1 R), a 44 kDa protein.

Purification: Ion Exchange Chromatography

Sterility: 0.22 μm filtered

Immunogen: U266 cell line

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate-buffered saline. Sterile-filtered through 0.22 μm and treated to remove endotoxins. Carrier and preservative free.

Preservative: Without preservative

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for CD28

Target: CD28

Alternative Name: CD28

Background: CD28 contains 1 Ig-like V-type (immunoglobulin-like) domain. Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.Synonyms: T-cell-specific surface glycoprotein CD28, TP44

Gene ID: 940

NCBI Accession: NP_006130

UniProt: P10747

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response