F11R antibody

Catalog No. ABIN1106264

The Rat Monoclonal anti-F11R antibody has been validated for FACS, IF and EIA. It is suitable to detect F11R in samples from Mouse.

Quick Overview for F11R antibody (ABIN1106264)

Target: F11R (F11 Receptor (F11R))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This F11R antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Clone: BV12

Product Details anti-F11R Antibody

Cross-Reactivity (Details): Species reactivity (tested):Mouse

Purification: Protein G

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: CD321 / JAM1

Background: JAM-A is a member of the immunoglobulin superfamily found on the surface of mouse platelets and at intercellular junctions of endothelial cells and epithelial cells. JAM-A belongs together with JAM-B (VE-JAM or JAM-3) and JAM-C (JAM-2) to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It codistributes with other tight junction components as ZO-1, 7H6 antigen, cingulin and occludin. In human JAM-A plays a role in platelet aggregation, secretion, adhesion and spreading.Synonyms: F11R, JAM-A, JCAM, Junctional adhesion molecule 1, Junctional adhesion molecule A, PAM1, Platelet F11 receptor, Platelet adhesion molecule 1

Pathways: Cell-Cell Junction Organization